androgen

(redirected from Adrenal androgen)
Also found in: Dictionary, Thesaurus, Medical.

androgen

(ăn`drəjən): see testosteronetestosterone
, principal androgen, or male sex hormone. One of the group of compounds known as anabolic steroids, testosterone is secreted by the testes (see testis) but is also synthesized in small quantities in the ovaries, cortices of the adrenal glands, and placenta, usually
..... Click the link for more information.
.

Androgen

One of a class of steroid hormones. Androgens play a major role in the development and maintenance of masculine secondary sexual characters, for example, the seminal vesicle and prostate gland of the male mammal, and the comb, wattles, and spur of the male fowl. They also influence certain other secondary sexual characters, such as hair growth pattern and voice quality in humans. In the fowl, they affect the pattern and seasonal coloration of its feathers, as well as crowing. In addition, androgens affect nitrogen metabolism (anabolic). Androgens are produced in the testis, ovary, adrenal, and most likely, in the placenta. A small portion of the androgen is from corticoids, or adrenal cortex steroids, and from other C21 steroids, such as progesterone. See Hormone, Ovary, Progesterone, Steroid, Testis

androgen

[′an·drə·jən]
(biochemistry)
A class of steroid hormones produced in the testis and adrenal cortex which act to regulate masculine secondary sexual characteristics.
References in periodicals archive ?
The clinical symptoms of CAH directly result from either the deficiencies in mineralocorticoid or glucocorticoid production or from the overproduction of adrenal androgens.
Regardless of the patient's BMI, those who present with symptoms of PCOS, including oligo- or amenorrhea, infertility, acne, hirsutism, or ovarian cysts, should receive a thorough workup including evaluation of ovarian and adrenal androgen hormones in addition to an assessment of insulin utility.
Adrenal androgens, DHEAS, DHEA, and androstenedione, contribute to 95% of the estrogenic activity in women and are responsible for more than 50% of the androgenic activity in women.
Dr Notelovitz pointed out that androgens may improve symptom relief in three ways: (1) by lowering sex hormone-binding globulin (SHBG) levels, which, in turn, results in a greater amount of bioavailable estrogen; (2) by a direct effect of androgens; or (3) by increased bioavailability of adrenal androgens (low adrenal androgen bioavailability may be induced by estrogen-alone therapy).
Similarly, in premenopausal women with adrenal androgen excess and insulin resistance, serum IGF-I concentrations are relatively high (49).
As an adrenal androgen, DHEA acts as a steroid precursor for gonadal and peripheral testosterone and estrogen production.
The hydrocortisone suppresses the production of adrenal androgens and stimulates the release of gonadotrophins if hypothalamic maturation is already present.
The results of this study show the benefits of marjoram tea in women with PCOS by reducing adrenal androgens and improving insulin sensitivity.
Moderately high levels of adrenal androgens and testosterone as well as sometimes a moderate elevation of 17-OH progesterone can also be associated with CAH.
Deficiency of 21-OH enzyme leads to overproduction and accumulation of precursors proximal to the blocked enzymatic step, deficient production of cortisol, increased ACTH, increased adrenal androgens and adrenal hyperplasia.
She also had low cortisol (and its precursors 17[alpha]-hydroxyprogesterone and 11-deoxycortisol), low adrenal androgens (DHEA sulfate and androstenedione), high mineralocorticoids precursors (11-deoxycorticosterone and corticosterone), high ACTH, and chromosomal analysis revealed a normal male karyotype 46 XY.
We found that DHEA-sulfate correlated with calculated BAT, perhaps reflecting that adrenal androgens and peripheral conversion to BAT may cause an elevation of BAT itself.