Chao, and P Casaccia-Bonnefil, "Lack of the cell-cycle inhibitor [p27.sup.Kip1] results in selective increase of transit-amplifying cells for adult neurogenesis
," The Journal of Neuroscience, vol.
in the DG was assessed using incorporation of 5-bromo-2'-deoxyuridine (BrdU) and was elevated in [alpha]-CaMKII HKO , FLX-treated , and pilocarpine-treated mice.
Sandeman, "Omega-3 fatty acids upregulate adult neurogenesis
," Neuroscience Letters, vol.
The main role of BDNF regarding adult neurogenesis
is not linked to proliferation, but to the increase in cell survival, as described using BDNF and its receptor TrkB knock-out animals which present a reduced BDNF expression [61, 169].
Several cell types are involved in adult neurogenesis
in the SVZ (Figure 3).
Winocur, "The effects of running and of inhibiting adult neurogenesis
on learning and memory in rats," European Journal of Neuroscience, vol.
was thought to originate from a specialized population of neural stem cells that were "set aside" and distinct from the precursors generating neurons during embryogenesis.
"Although exercise-induced adult neurogenesis
improved cognition in Alzheimer's mice by turning on neurogenesis, trying to achieve that result by using gene therapy and drugs did not help," Dr.
Alvarez-Buylla's lab responded to the latest research in a statement saying that they were unconvinced Columbia University had found conclusive evidence of adult neurogenesis
littoralis on adult neurogenesis
in the DG of the adult mouse hippocampus using 5-bromo-2-deoxyuridine (BrdU, an indicator for cell proliferation) labeling and immunohistochemistry for doublecortin (DCX, an immature neuronal marker), which has been commonly used to investigate the proliferation of neuroblast., In addition, we examined expressional changes of brain-derived neurotrophic factor (BDNF) and its major receptor tropomyosin-related kinase B (TrkB), which are well known to be involved in the neurogenic process.,
With regards to adult neurogenesis
, Decressac et al.