African sleeping sickness


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African sleeping sickness

[′af·ri·kən ′slēp·iŋ ′sik·nəs]
(medicine)
A disease of humans confined to tropical Africa, caused by the protozoans Trypanosoma gambiense or T. rhodesiense; symptoms include local reaction at the site of the bite, fever, enlargement of adjacent lymph nodes, skin rash, edema, and during the late phase, somnolence and emaciation. Also known as African trypanosomiasis; maladie du sommeil; sleeping sickness.
References in periodicals archive ?
Vice President and Chief Medical Officer stated, "Successfully completing pafuramidine's Phase III interim analysis is a major milestone on the path to registering pafuramidine for treatment of African sleeping sickness.
Scientists have deciphered the DNA of the parasites responsible for three deadly diseases: African sleeping sickness, Chagas' disease, and leishmaniasis.
However, Immtech believes that the potential risk associated with further treatment of African sleeping sickness patients outweighs the benefits of further development because these patients are generally located in places where medical care may not be readily available.
The parasite that causes African sleeping sickness can't survive in the mammalian bloodstream without its tail, scientists report.
The new test exploits the common heritage of the parasites that cause Chagas, leishmaniasis, and African sleeping sickness.
For example, he describes the discovery of the African sleeping sickness agent, Trypanosoma gambiense, and the contributions in the early 1900s by Dutton, Castellani, and Bruce.
Neglected diseases are defined as diseases that disproportionately affect the world's poorest people, including tuberculosis or TB, malaria, visceral leishmaniasis, Chagas disease, human African trypanosomiasis or African sleeping sickness, and filarial worm diseases such as onchocerciasis and lymphatic filariasis.
Washington, May 11 (ANI): Scientists in France have discovered a new bacterial species in the gut of the fly that transmits African sleeping sickness.
It might work against the T bruce/ variation that causes the more virulent East African sleeping sickness and might also kill the parasite responsible for Chagas disease, Trypanosoma cruzi, Olson says.
She sees the bad blood in her body as an extended metaphor constructing a fever that makes her progressively weak and lethargic as if she had African sleeping sickness, the thing perhaps taking the edge off, numbing the painful feelings like an epidural.
The Company expects to enter DB289 into Phase II human trials for treating PCP and African sleeping sickness later this year.
Immtech has advanced clinical programs that include new treatments for Pneumocystis pneumonia, malaria and African sleeping sickness (Trypanosomiasis) and drug development programs for fungal infections, hepatitis C, and other indications.

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