agonist

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Related to Agonists: Partial agonists

agonist

[′ag·ə‚nist]
(biochemistry)
A chemical substance that can combine with a cell receptor and cause a reaction or create an active site.
(physiology)
A contracting muscle that is resisted or counteracted by another muscle, called an antagonist, with which it is paired.
References in periodicals archive ?
Administration of RORgamma agonists in syngeneic tumor models resulted in immune-dependent inhibition of tumor growth compared to vehicle controls.
compared the flare-up versus the long GnRH agonist regimen, and observed higher pregnancy and lower cancellation rates with the flare-up protocol (6).
Despite of the diversity in response [for details, see Supplemental Material, "Structural diversity assessment of apparent NR agonists and antagonists," and Supplemental Material, Figure 3 (doi: 10.
What is less clear is whether GnRH agonists alter cardiovascular mortality.
Adolor and Pfizer Inc (NYSE:PFE) are collaborating on the worldwide development and commercialization of two novel Delta opioid agonist compounds, ADL5859 and ADL5747, for the treatment of pain.
Two of the four studies that addressed pulsatility as a measure of blood flow showed that [alpha]-1 agonists were associated with a transient increase in the pulsatility index, but this effect did not appear to affect fetal outcomes.
Piping an agonist into the accumbens that targets a specific dopamine receptor, the D2, proved particularly effective at preventing withdrawal symptoms.
The primary role of anti-inflammatory medications, and the secondary or backup use of beta-2 agonists and other bronchodilating medications, have been carefully outlined in the [pamphlet] Guidelines on the Diagnosis and Management of Asthma'.
Physicians may be shifting away from prescribing PPAR-gamma agonists in favor of DPP-IV inhibitors because of safety concerns with PPAR-gamma agonists and growing familiarity with the DPP-IV inhibitor class," said BioTrends Director Nicole Westphal, Ph.
Schally and his colleagues showed that GHRH agonists could positively influence the growth, function and engraftment of islet cells in preclinical models.
Zanettini and colleagues noted the presence of increased mitral tenting, a geometric measure of the position of the leaflets that can be an early indicator of valvular dysfunction, in patients receiving ergot-derived dopamine agonists such as pergolide and cabergoline.
The report provides a compilation of current active projects in research and development of novel PPAR agonists.