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(myocardosis), a term often applied to a broad group of heart diseases; specifically, noninflammatory lesions of the heart muscle (myocardium) resulting from a disturbance in myocardial metabolism. Among the causes of cardiomyopathy are nutritional disorders (alimentary dystrophy and avitaminosis, for example); protein metabolism disorders in hepatic or renal insufficiency and podagra; disturbances of carbohydrate metabolism (diabetes mellitus) and electrolyte metabolism; and endocrine disorders such as those associated with thyrotoxicosis and with hypoxia in impairment of coronary circulation, anemia, and mountain sickness. Myocardosis may also be caused by overstraining the myocardium and by exogenous poisons, such as carbon monoxide and alcohol.

In many cases the patient has no specific symptoms in the early stages; however, there may be shortness of breath and disagreeable sensations in the heart. Cardiomyopathy is manifested by dull, distant heart sounds, electrocardiographic changes, systolic murmur, extrasystole, and, more rarely, other types of arrhythmia. Severe cardiomyopathy weakens the heart contractions and may cause cardiac insufficiency. The changes associated with cardiomyopathy are usually reversible and disappear with the elimination of the underlying disease.

The cure includes treatment of the underlying disease and administration of agents that improve metabolic processes in the myocardium.


Kedrov, A. A. Bolezni myshtsy serdtsa. Leningrad, 1963.


References in periodicals archive ?
Alcoholic cardiomyopathy (ACM) is a heart-muscle disease found in individuals with a history of long-term heavy alcohol consumption.
Comparison of alcoholic cardiomyopathy in women versus men.
In general, initial signs of Alcoholic cardiomyopathy (ACM) appear to be increased left ventricular mass along with increased posterior and septal wall thickening.
There are many studies verifying the adverse effects of chronic alcohol consumption on the function of mitochondria and sarcoplasmic reticulum function which could be another cause of alcoholic cardiomyopathy.
2005), and research with dogs has shown that oral nicotine administration increases the degree of scarring that accompanies alcoholic cardiomyopathy (Rajiyah et al.
Since, in the present study, the sole cause of dilatation in heart chambers was alcohol, it can be labelled as alcoholic cardiomyopathy.
Alcoholic cardiomyopathy accounts for 33% of all dilated cardiomyopathies.
Deaths Alcohol-attributable condition Male Female Total Lip & Oropharyngeal Cancer 173 38 211 Oesophageal Cancer 304 65 370 Liver Cancer 171 63 234 Laryngeal Cancer 170 17 186 Breast Cancer 0 189 189 Alcoholic Psychoses 46 6 52 Alcohol Dependence Syndrome 416 117 533 Alcohol Abuse 70 21 91 Epilepsy 21 16 37 Alcoholic Polyneuropathy 0 0 0 Hypertension 23 7 30 Alcoholic Cardiomyopathy 69 4 73 Cardiac Dysrhythmias 56 48 103 Heart Failure & III-defined 8 5 12 Stroke 142 12 153 Oesophageal Varices 5 1 61 Gastro-oesophag.
Long-term heavy drinking can cause the heart to become enlarged and lose some of its ability to contract, a condition known as alcoholic cardiomyopathy.
binge) and long-term drinking can interfere with the function of the heart, a condition referred to as alcoholic cardiomyopathy.
The most convincing circumstantial evidence for alcoholic cardiomyopathy is the extensive data, in animals and humans, of nonspecific cardiac abnormalities related to alcohol.