spironolactone

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spironolactone

[′spī·rə·nō′lak‚tōn]
(pharmacology)
C24H32O4S A steroid having a lactone ring attached at carbon-17; used as a diuretic.
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The side-effects of aldactone include anti-androgenic effects through the antagonism of dihydrotestosterone at its binding site.
The effect of spironolactone on morbidity and mortality in patients with severe heart failure: Randomized Aldactone Evaluation Study Investigators.
In fact, because of the teratogenic effects of aldactone and because metformin can induce ovulatory cycles, if these medications are used, all sexually active females should be encouraged to take a COC concurrently.
That includes those who take medications that hinder potassium excretion (like the diuretics Aldactone, Midamor, and Dyrenium) and those--especially diabetics--who have impaired kidney function.
Commonly used diuretics include hydrochlorothiazide, Lasix, Dyazide, and Aldactone.
By dilating blood vessels and easing the heart's workload, these drugs (along with diuretics) became the standard treatment for CHF--and Aldactone was relegated to the museum of ancient remedies.
In android-shaped women with very high levels of males hormones, prescribed drugs are an oestrogenic contraceptive pill, Aldactone or Androcur.
s daily medications except his insulin pump therapy and Aldactone.
Spironolactone labored in near obscurity for years, following approval in 1960 as Aldactone, a treatment for primary hyperaldosteronism.
Aldactone is the diuretic of choice but there can be complications which can be looked into.
She was, however, on 13 outpatient medications: Lantus, Singulair, aspirin, Niferex, Toprol, Lasix, Zestril, Lipitor, propoxyphene, Aldactone, Plavix, Prilosec, and Cardizem, as well as home oxygen.
In the Randomized Aldactone Evaluation Study (RALES), (16) patients with severe heart failure (ejection fraction <35%) on standard medical therapy were randomized to receive spironolactone or placebo (LOE: 1).