(2015) East asian variant of aldehyde dehydrogenase
2 is associated with coronary spastic angina: Possible roles of reactive aldehydes and implications of alcohol flushing syndrome.
Dietary ethanol mediates selection on aldehyde dehydrogenase
activity in Drosophila melanogaster.
The effect of salt on betaine aldehyde dehydrogenase
transcript levels and 2-Acetyl-1-pyrroline concentration in fragrant and non-fragrant rice (Oryza sativa, L.).
Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase
Deficient activity of the fatty aldehyde dehydrogenase
component of fatty alcohol: NAD+ oxidoreductase in cultured fibroblasts," Journal of Clinical Investigation, vol.
Jakoby, " Aldehyde dehydrogenase
from baker's yeast," Methods in Enzymology, vol.
2 (ALDH2) is a homotetramer enzyme located in the mitochondrial matrix.
2 (ALDH2) polymorphism gene and coronary artery disease risk: a meta-analysis.
Key words: Alcohol dependence; alcohol use disorder (AUD); alcohol metabolism; alcohol-metabolizing enzymes; genetic factors; environmental factors; biological factors; gene variants; alcohol dehydrogenase (ADH); aldehyde dehydrogenase
(ALDH); alleles; acetaldehyde; Asians; Caucasians; Africans; Asian-American; African-American
It has been assumed in early case reports that metronidazole caused a similar interaction with alcohol and raised acetaldehyde levels by interfering with aldehyde dehydrogenase
The main ethanol biotransformation reaction is catalysed by alcohol dehydrogenase (ADH) and is performed in the cytoplasm, where this enzyme oxidises the ethanol producing acetaldehyde, which in turn is oxidized by the enzyme aldehyde dehydrogenase
(ALDH) to acetate.
The following enzymes are known to contribute or have a direct role in metabolism of histamine: monoamine oxidase (MAO), di amine oxidase (DAO), and histamine N-methyl transferase, aldehyde dehydrogenase
. (4, 5, 6, 7, 8, 9) Each of these enzymes play specific roles.