interleukin-2

(redirected from Aldesleukin)
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Related to Aldesleukin: Proleukin

interleukin-2

[‚in·tər¦lük·ən ′tü]
(immunology)
A lymphokine secreted mostly by helper T lymphocytes that promotes the growth of T lymphocytes. Abbreviated IL-2.
References in periodicals archive ?
Drug class Drug Pharmacology Aldesleukin Recombinant interleukin-2 Ipilimumab CTLA-4 inhibitors Immunomodulators Nivolumab PD-1 inhibitors Pembrolizumab PD-1 inhibitors Denileukin Recombinant interleukin-2 and diphtheria toxin Drug class Drug References Total Mortality Aldesleukin [81, 82] 2 1 Ipilimumab [83] 1 0 Immunomodulators Nivolumab [84, 85] 2 1 Pembrolizumab [86, 114, 116] 4 0 Denileukin [87] 1 Total 9 3 Drug class Drug SJS SJS/TEN TEN Aldesleukin 0 0 2 Ipilimumab 1 0 0 Immunomodulators Nivolumab 0 0 2 Pembrolizumab 4 0 0 Denileukin 0 0 1 5 0 5
In spite of numerous restrictions and warnings, a recombinant modified version of IL-2 (aldesleukin) was approved in 1992 for metastatic RCC and in 1998 for metastatic melanoma patients [4].
* Proleukin (aldesleukin; Novartis): Which two barriers do more doctors experience with Proleukin than any other brand?
Patients received lymphocyte-depleting chemotherapy before ACT and aldesleukin chemotherapy injection after ACT.
The High-Dose Aldesleukin (IL-2) "Select" Trial for Patients With Metastatic Renal Cell Cancer (SELECT).http://clinicaltrials.govict2/show/NCT00554515.