Aldolase


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aldolase

[′al·də‚lās]
(biochemistry)
An enzyme in anaerobic glycolysis that catalyzes the cleavage of fructose 1,6-diphosphate to glyceraldehyde 3-phosphate; used also in the reverse reaction.

Aldolase

 

an enzyme; one of the lyases, which split and synthesize carbon bonds (—C—C—). Its molecular mass is 147,000–180,000; the aldolase molecule is composed of two polypeptide chains. In animals aldolase is generally found in the skeletal muscles; in plants it is found in areas where photosynthesis takes place. Aldolase condenses aldehydes; this is the derivation of the name. It is catalyzed by a reversible reaction: fructose diphosphate ⇌ 3–phosphoglycerine aldehyde + phosphodioxyacetone. In plant tissues aldolase takes part in the dark phase of photosynthesis; in animals, in the process of glycolysis, which leads to the production of such energy-rich compounds as ATP.

References in periodicals archive ?
However, before discharge on day 6, thick blood film examination was still positive (192/[micro]L), but by day 11, his repeat blood film examination and his aldolase rapid diagnostic test results were negative.
The primary structures of the pseudogenes derived proteins showed very high sequence identity (<83%) with other bacterial enzymes such as aldolases, synthase, and transposases (Table S1), suggesting that these genes can produce active proteins if transcribe.
The membrane is precoated with anti-HRP 2 specific antibodies for plasmodium falciparum and plasmodium specific anti aldolase antibodies for the detection of other three species of plasmodium.
faecalis identification was confirmed by PCR for the eda1 gene (encoding 2-keto-3-deoxy-6-phosphogluconate aldolase, which is an enzyme involved in the Entner-Doudoroff pathway and is species-specific for E.
Serum biochemical parameters (glucose, urea, uric acid, creatine kinase, creatin kinase, lactate dehydrogenase, aspartate transaminase, alanine transaminase, aldolase, total proteins, cholesterol and electrolytes) were measured using coupled enzyme reactions on an automatic autoanalyzer (Hitachi 917, Japan).
Serum levels of CK and aldolase, both representing myogenic enzymes that serve as serum markers for dermatomyositis, were increased to 2621 U/L and 19.
The glycolytic enzyme aldolase was thought to be the link between actin and surface adhesins (reported in Mol Cell).
28) The necrosis of muscle can be confirmed by the detection of keratin kinas, lactate dehydrogenase, amino-transferees and aldolase.
Differentially expressed proteins in the cerebellum were related to growth functions associated with carbohydrate metabolism [alpha-enolase (ENOA) and fructose-bisphosphate aldolase C (ALDOC)] and RNA processing [heterogeneous nuclear ribonucleoprotein (HNR) H2 and heterogeneous nuclear ribonucleoprotein A3 (ROA3)] (see Supplemental Material, Table S2).
Creatine kinase was normal, and aldolase was found to be 9.