allele frequency


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Related to allele frequency: Genotype frequency

allele frequency

[ə′lēl ¦frē·kwən·sē]
(genetics)
The fraction of all alleles at a given locus constituted by a particular allele in a population. Also known as gene frequency.
References in periodicals archive ?
Hardy-Weinberg equilibrium (HWE) was calculated for single nucleotide polymorphism (SNP) data which was analysed for genotype and allele frequency determination by applying chi-squared statistics.
Across sampling schemes only UCO showed significant bottlenecks under the Wilcoxon test; East Arcadia showed a significant Wilcoxon value for the historical allele frequency sampling.
For the c.114T>G polymorphism of MITF, the T allele frequency (0.352) was considerably higher in the black-colored duck population than in the white-colored ducks (0.144).
All Healthy Subjects N 290 90 Age (years) 54.4 (15.1) 43.1 (11.9) Sex (male) 53.5% 46.6% BMI (Kg/[m.sup.2]) 28.8 (5.3) 25.2 (4.6) T2DM 41.6% 7% PNPLA3 G allele frequency 0.46 0.24 TM6SF2 T allele frequency 0.11 0.06 KLF6 T allele frequency 0.08 0.06 SOD2 T allele frequency 0.5 0.48 LPIN1 T allele frequency 0.32 0.35 Noncirrhotic NAFLD NASH cirrhosis N 93 107 Age (years) 51.6 (13.2) (++) 66.2 (9.8) (++) ** Sex (male) 60.2% 53.30% BMI (Kg/[m.sup.2]) 29.5 (4.1) (++) 31.2 (5.2) (++) * T2DM 45.2% (++) 66.4% (++) * PNPLA3 G allele frequency 0.48 (++) 0.61 (++) * TM6SF2 T allele frequency 0.11 0.14 (+) KLF6 T allele frequency 0.07 0.12 SOD2 T allele frequency 0.53 0.49 LPIN1 T allele frequency 0.32 0.31 Data are shown as mean (standard deviation) or percentages.
Bonferroni correction was carried out by only taking into account alleles with allele frequency greater than 5% to compensate for overcorrection.
The allele frequency of F was 73.86% and that of was 26.31%.
Results: Cytosine-cytosine and cytosin-thymine genotype frequencies of the TLR2 R753Q single nucleotide polymorphism in the atopic dermatitis group were determined as being 98.6% and 1.4%, cytosine allele frequency for TLR2 R753Q single nucleotide polymorphism was determined as 99.29% and the thymine allele frequency was 0.71%, thymine-thymine, thymine-adenine, and adenine-adenine genotype frequencies of the TLR2 A-16934T single nucleotide polymorphism were 24.3%, 44.3%, and 31.4%.
For a genotype and allele frequency analysis, a total of 400 T2DM patients and 200 healthy subjects were enrolled.
The PECAM-1 + 1688 A/G polymorphisms tested in this study failed to show any significant associations with genotype or allele frequency in KD patients compared with those of controls (genotype: [chi square] = 0.24, P = 0.887; allele frequency: [chi square] = 0.04, P = 0.836) (Table 3).