alloxan

(redirected from Alloxane)
Also found in: Dictionary, Medical.

alloxan

[ə′läk·sən]
(biochemistry)
C4H2N2O4 Crystalline oxidation product of uric acid; induces diabetes experimentally by selective destruction of pancreatic beta cells. Also known as mesoxyalyurea.
References in periodicals archive ?
Experimental diabetes was induced by single subcutaneous alloxane administration in dose of 150 mg/kg (Baranov, 1983).
Analysis shows that alloxane, first of all, has selective effect on the [beta]-cells of the Langerhans islets.
dystrophy and necrosis in the liver and pancreatic gland occurring in alloxane diabetes, and stimulates reparative processes in studied organs.