(redirected from Alpha Thalassaemia)
Also found in: Dictionary, Thesaurus, Medical.
Related to Alpha Thalassaemia: hemoglobin H, Alpha Thalassemia


A hereditary form of hemolytic anemia resulting from a defective synthesis of hemoglobin: thalassemia major is the homozygous state accompanied by clinical illness, and thalassemia minor is the heterozygous state and may not have evident clinical manifestations. Also known as Mediterranean anemia.



(also thalassanemia), a familial hemolytic anemia, first detected in 1925 among inhabitants of the Mediterranean region. Thalassemia is caused by disturbances in hemoglobin synthesis.

References in periodicals archive ?
Doctors diagnosed him as suffering from Alpha Thalassaemia, known as ATRX syndrome.
XmnI polymorphism, the T-allele in linkage to the haplotype I and coinheritance of alpha thalassaemia gene) were found to predict a response in these studies.