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Related to Alpha Thalassaemia: hemoglobin H, Alpha Thalassemia


A hereditary form of hemolytic anemia resulting from a defective synthesis of hemoglobin: thalassemia major is the homozygous state accompanied by clinical illness, and thalassemia minor is the heterozygous state and may not have evident clinical manifestations. Also known as Mediterranean anemia.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



(also thalassanemia), a familial hemolytic anemia, first detected in 1925 among inhabitants of the Mediterranean region. Thalassemia is caused by disturbances in hemoglobin synthesis.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The molecular basis of alpha thalassaemia in a South African population.
"I'm thrilled that it was safe and it was feasible," MacKenzie said, adding it was also important "to get the message out that foetal transfusions for alpha thalassaemia are lifesaving." She expects to perform transplants on a few more patients, see how they fare and then decide how to proceed.
Haemoglobin J Tongariki is associated with alpha thalassaemia. Nature 1978; 273: 319-20.
XmnI polymorphism, the T-allele in linkage to the haplotype I and coinheritance of alpha thalassaemia gene) were found to predict a response in these studies.7-9