is caused by mutations in the alpha globin gene locus on chromosome 16.
showed that coinheritance of alpha thalassemia
with homozygous beta thalassemia resulted in melioration of the beta thalassemia.
This finding is similar to the results of the work of Old and colleagues, where combination of a certain type of Hb-J (Hb J-Tongariki) and alpha thalassemia
robustly affected the red cell indices.
A test called mutational analysis can help detect alpha thalassemia
that cannot be seen with hemoglobin electrophoresis.
The severity of alpha thalassemia
is correlated with the number of affected globin loci:
Although the incidence studies of alpha thalassemia
in Turkey are rare, more frequently hemoglobin H disease has been observed in south of Turkey, The molecular basis of Hb H disease was studied and mutations - [alpha]3.
In conclusion, the results suggest that anaemia among Ahvaz adolescent schoolgirls cannot be solely explained by iron deficiency although it consist about half of patient and other causes like alpha thalassemia
and beta thalassemia may play significant role in anemic students.
9), 1 had alpha thalassemia
alone, 1 had coexisting alpha-thalassemia and hemoglobin AS, and 1 had hemoglobin SC.
An association between hypertension and the "silent carrier" state for alpha thalassemia
Kan applied this discovery to the development of a DNA test that was used successfully in 1976 to diagnose alpha thalassemia
in an unborn fetus.
7) Both HPLC and CE can detect alpha thalassemia
in newborns, since various levels of Hb Barts (depending on the number of alpha-gene deletions) will be present in the sample.
Concurrence of hereditary spherocytosis and alpha thalassemia