AAT

(redirected from Alpha-1-Antitrypsin)
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AAT

Abbrev. for Anglo-Australian telescope.
References in periodicals archive ?
The inhibition of the proteolytic activity protects the lung.[5] Several studies reported that the Alpha-1-antitrypsin ( Alpha-1-AT ) deficiency was significantly associated with the incidence of pulmonary emphysema.[6] In addition, one study estimated that about 1-2% of COPD might be caused by genetic deficiency in Alpha-1-AT .[7] However, the evidence is limited, as only a few epidemiological studies have explored the relationship between Alpha-1-AT gene polymorphism and COPD.
Jardi, "Rare alpha-1-antitrypsin variants: Are they really so rare?" Therapeutic Advances in Respiratory Disease, vol.
Alpha-1-antitrypsin (AAT), also known as SERPINA1 (serine protease inhibitor, group A, member 1), is a secreted protein produced mainly by hepatocytes and to a smaller extent by mononuclear phagocytes, neutrophils, and airway/intestinal epithelial cells [5, 8].
Aroori, "Delayed diagnosis of alpha-1-antitrypsin deficiency following post-hepatectomy liver failure: a case report," World Journal of Gastroenterology, vol.
Interestingly, during the Kasai reconstruction, the results of the serum alpha-1-antitrypsin analysis returned at 36mg/dL, positive for alpha-1-antitrypsin disease.
Charactrization of the gene and protein of the common alpha-1-antitrypsin normal M2 allele.
The patents cover the production of several recombinant proteins, including Alpha-1-Antitrypsin, Factor IX, and others.
Clinical features and history of the destructive lung disease associated with alpha-1-antitrypsin deficiency of adults with pulmonary symptoms.
There are a relatively small number of people, however, who get severe emphysema due to a deficiency of alpha-1-antitrypsin, a substance normally found in the blood and lungs.
Normally, after the proteases complete their work in the lung, they are inhibited by a protein called alpha-1-antitrypsin. But sometimes alpha-1-antitrypsin is missing or inactivated.
A natural protein called alpha-1-antitrypsin defends the lungs against damage by the enzyme elastase.
Kamada announced receipt of a letter from the FDA stating that the company has satisfactorily addressed the concerns and questions regarding its inhaled Alpha-1-Antitrypsin, or Inhaled AAT, program for the treatment of Alpha-1 Antitrypsin Deficiency, or AATD, previously communicated by the FDA.

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