actin

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Related to Alpha-actin: actin filament, Thin filament

actin

actin, a protein abundantly present in many cells, especially muscle cells, that significantly contributes to the cell's structure and motility. Actin can very quickly assemble into long polymer rods called microfilaments. These microfilaments have a variety of roles—they form part of the cell's cytoskeleton, they interact with myosin to permit movement of the cell, and they pinch the cell into two during cell division. In muscle contraction, filaments of actin and myosin alternately unlink and chemically link in a sliding action. The energy for this reaction is supplied by adenosine triphosphate.
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actin

[′ak·tən]
(biochemistry)
A muscle protein that is the chief constituent of the Z-band myofilaments of each sarcomere.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Note increased expression of alpha-actin of smooth muscle around the acini and increase of type I collagen in the stroma of obese mice.
The submucous layer was thickened with an increased number of Cajal cells, and there was thick, high-density collagen IV and alpha-actin. The muscular layers were hypertrophic and the vessels were significantly ectatic.
The research team led by Dianna Milewicz, professor and director of the Division of Medical Genetics at The University of Texas Medical School at Houston has found that mutations in n smooth muscle alpha-actin (ACTA2) cause early onset coronary artery disease, stroke and moyamoya disease, along with thoracic aortic aneurysms and dissections.