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ANTIHYPERTENSIVES: A group of medications, originally used as antihypertensives, are the alpha-agonists clonidine (Catapres), and guanfacine (Tenex).
Adding an alpha-agonist to an antipsychotic also can "be enough to knock out a tic substantially," he said.
For children with attention-deficit/hyperactivity disorder (ADHD), 81% of psychiatrists prescribed an alpha-agonist such as clonidine, compared with 67% who prescribed an alpha-agonist for mental retardation/developmental delay (MR/DD) and autism spectrum disorders, 40% who prescribed a drug in this class for anxiety disorders, and 31% who prescribed it for mood disorders.

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