Erroneous determination of hyperphosphatemia ('pseudohyperphosphatemia') in sera of patients that have been treated with liposomal amphotericin B (AmBisome
Pursuant to the agreement, Mylan will market and distribute in India Gilead's AmBisome
(amphotericin B liposome for injection), a treatment for life-threatening, systemic fungal infections, which is also used to treat the parasitic disease visceral leishmaniasis.
Mylan's distribution agreement in India also includes Gilead's AmBisome
(amphotericin B liposome for injection) for life-threatening, systemic fungal infections and the parasitic disease visceral leishmaniasis as well as Viread for chronic hepatitis B virus (HBV) infections.
Most of the currently available AmB nanoformulations are lipidbased (Ambisome
, Amphocil, and Abelcet) though some are also available in micellar (Fungizone) and nanosuspension form .
Food and drug administration approval of AmBisome
(liposomal amphotericine B) for treatment of visceral leishmaniasis.
It has been documented in a number of studies that AmBisome
is a suitable drug for treatment of PKDL ([26, 28], unpublished data).
For Visceral Leishmania, liposomal amphotericin and Pentostam is suggested but the drug of choice is Ambisome
In the Indian subcontinent, where VL is endemic, the WHO Leishmaniasis Expert Committee recommends single-dose AmBisome
as the safest, most effective treatment for the disease.
At that time, the physician then added amphotericin B (Ambisome
), rifampin (Rifadin), azithromycin (Zithromax), and fluconazole (Diflucan) to the medication regimen.
Maes, L., Germonprez, N., Quirijnen, L., Van Puyvelde, L., Cos, P., Vanden Berghe, D., 2004, Comparative activities of the triterpene saponin maesabalide III and liposomal amphotericin B(AmBisome
) against Leishmania donovani in hamsters.
(liposomal amphotericin B) (product monograph) [electronic version].
Amphotericin B (ambisome
) * administration Schedule a.