Chagas Disease

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Related to American trypanosomiasis: African trypanosomiasis, leishmaniasis

Chagas’ Disease


(also called American trypanosomiasis), a transmissible parasitic disease of humans and animals caused by trypanosomes. The disease was described in 1909 in Brazil (state of Minas Gerais) by the physician C. Chagas. It occurs in Central and South America, chiefly among the poorest strata of the population, who live in dwellings infested by transmitters of the disease (bloodsucking hemipterous insects, mainly triatomids). Humans and wild and domestic animals suffering from Chagas’ disease are the sources of infection.

Infection occurs when the causative agent, together with insect feces, enters injured skin or the mucous membranes of the eyes, nose, and mouth. The main symptoms are fever and enlargement of the lymph nodes in the acute stage, with involvement of the heart and gastrointestinal tract when the disease becomes chronic. The main methods for controlling Chagas’ disease are improvement of social and living conditions of the people, disinsectization, and destruction of infected animals.

References in periodicals archive ?
Because autochthonous vector-borne cases of American trypanosomiasis are relatively rare in the United States, only limited population studies on the presence of T.
American trypanosomiasis (Chagas's disease): first indigenous case in the United States.
Fiocruz is one of the world's leading centers for the study of Chagas disease, also known as American trypanosomiasis.
It ended a 20-year epoch in which arthropods were found to be the vectors of major diseases of animals and humans, including not only typhus but also African trypanosomiasis, American trypanosomiasis, dengue, filariasis, malaria, relapsing fever, Texas cattle fever, and yellow fever.
American trypanosomiasis (Chagas' disease); first indigenous case in the United States.
Participants also discussed current trends and challenges of protozoan parasitic zoonoses, including cryptosporidiosis, toxoplasmosis, African and Latin American trypanosomiasis, and leishmaniasis.
cruzi DNA detected by PCR in a population at high risk for chronic American trypanosomiasis.
In addition, this physiologic compensation generates an increase in illness and death from other infections that require a protective Th1 response as, for example, tuberculosis, malaria, American trypanosomiasis, leishmaniasis, toxoplasmosis, lysteriosis, and pneumocystosis.

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