Chagas Disease

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Related to American trypanosomiasis: African trypanosomiasis, leishmaniasis
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Chagas’ Disease

 

(also called American trypanosomiasis), a transmissible parasitic disease of humans and animals caused by trypanosomes. The disease was described in 1909 in Brazil (state of Minas Gerais) by the physician C. Chagas. It occurs in Central and South America, chiefly among the poorest strata of the population, who live in dwellings infested by transmitters of the disease (bloodsucking hemipterous insects, mainly triatomids). Humans and wild and domestic animals suffering from Chagas’ disease are the sources of infection.

Infection occurs when the causative agent, together with insect feces, enters injured skin or the mucous membranes of the eyes, nose, and mouth. The main symptoms are fever and enlargement of the lymph nodes in the acute stage, with involvement of the heart and gastrointestinal tract when the disease becomes chronic. The main methods for controlling Chagas’ disease are improvement of social and living conditions of the people, disinsectization, and destruction of infected animals.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
KEGG mapping analysis also identified disease-related KEGG pathways characterised by liver dysfunction, such as malaria, Chagas disease (American trypanosomiasis), Salmonella infection, and Legionellosis.
[2] PAHO, Chagas Disease (American Trypanosomiasis), Regional Office for the Americas of the World Healthg Organization, Washington, DC, USA, 2014.
It is vital that a mechanism is in place to allow physicians working in nonendemic areas who are involved in the management of patients from trypanosomiasis-endemic areas to have access to suramin and several other essential but rarely used agents (such as melarsoprol, eflornithine, nifurtimox, and benznidazole; the last two drugs used for treatment of South American trypanosomiasis) from a central repository 24 hours a day, 7 days a week.
American trypanosomiasis in a dog from Argentinean northeast.
[USPRwire, Sun Dec 20 2015] Global Markets Direct's, 'Chagas Disease (American Trypanosomiasis) - Pipeline Review, H2 2015', provides an overview of the Chagas Disease (American Trypanosomiasis)'s therapeutic pipeline.
AMERICAN TRYPANOSOMIASIS, which the World Health Organization characterizes as one of the globe's neglected diseases, currently affects about eight million people.
Neglected Tropical Diseases include Chagas disease, also known as American trypanosomiasis. There are approximately 15mn people in the Americas with this disease which, although it doesn't kill victims rapidly, it causes years of debilitating symptoms; dengue fever, of which there are 50-100mn cases annually which can lead to a serious and potentially fatal form called severe dengue; echinococcosis, of which there are more than 1mn people infected; leishmaniasis, which is fatal if untreated and of which there are an estimated 12mn people infected and onchocerciasis, also known as "river blindness" of which there are 37mn people infected, just to mention a few of them.
Neglected Tropical Diseases include Chagas disease, also known as American trypanosomiasis. There are approximately 15 million people in the Americas with this disease, which, although it doesn't kill victims rapidly, causes years of debilitating symptoms.
Neglected Tropical Diseases include Chagas disease, also known as American trypanosomiasis. There are approximately 15 million people in the Americas with this disease which, although it doesn't kill victims rapidly, it causes years of debilitating symptoms; dengue fever, of which there are 50-100 million dengue fever infections annually which can lead to a serious and potentially fatal form called severe dengue; echinococcosis, of which there are more than 1 million people infected; leishmaniasis, which is fatal if untreated and of which there are an estimated 12 million people infected and onchocerciasis, also known as "river blindness" of which there are 37 million people infected, just to mention a few of them.

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