amidation


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amidation

[‚am·ə‚dā·shən]
(organic chemistry)
The process of forming an amide; for example, in the laboratory benzyl reacts with methyl amine to form N-methylbenzamide.
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Type text or a website address or If excess acid is used, it will be a drastic decrease of the viscosity, and excess acid will act as a solvent for salt (6), but the observations made generally found that amidation reaction will be reduced if given excess acid (7,12).
Oleic acid was subjected to amidation by monoethanol amine for comparison under the same conditions.
Thus, the extensive research has been focused on the functionalization of CNTs which can be cited fluorination (Pourrezar et al., 2009), carbene addition (Malic et al., 2010), esterification (Hu et al., 2004) and amidation (Venkatesan et al., 2005).
aureus strains, namely the amidation of the a-carboxyl of D-[Glu.sup.2] to form D-[iGln.sup.2] and the addition of a pentaglycine side chain on the [epsilon]-amino group of L-[Lys.sup.3] by the Fem amino-acyltransferases (9).
It is well recognized that vitamin C plays a significant role in the growth (Ai et al., 2006; Zhou et al., 2012) by enhancing collagen and carnitine biosynthesis (Aysun, 2009), amidation of peptide hormones (Jimenez-Fernandez et al., 2012), metabolism of iron (James, 2001) and immunity (Anbarasu and Chandran, 2001; Ai et al., 2006) or by acting as a resistant modulator (Tewary and Patra, 2008; Eo and Lee, 2008).
Presently, C-terminal peptide amidation poses a challenge in pharmaceutical production due to limitations of the two enzymes used for this purpose.
Lastly, posttranslational amidation of the C-terminal amino acid is also essential for NmU activity, because deamidated forms are unable to induce smooth muscle contraction or intracellular [Ca.sup.2+] influx (9, 13, 14).
Amdiation of the C-terminus was shown to accelerate IAPP amyloid formation relative to the variant with a free C-terminus, even though amidation increased the net charge on the polypeptide.
However, the origin and structural characteristics of the novel myotropic peptide, an internal -PPW- sequence and C-terminal amidation, indicated that it was a member of the amphibian skin tryptophyllin family, subtype T-2, and thus it was named Agalychnis callidryas tryptophyllin-2 (AcT-2) in accordance.
HN[O.sub.3]) which generates substitutable hydrophilic functional groups such as COOH and OH on the CNTs which then further undergo into the chemical reactions such as esterification, amidation, chlorination, bromination, hydrogenation, and Diel's-Alder reaction.
Armadillidin is a glycine rich, cationic antimicrobial peptide with unique fivefold repeated motifs of GGGFHR or GGGFHS and amidation at the C-terminal end that displayed potent antibacterial activity against Gram-positive bacteria [33].
(6) Amidation, which arose from condensation reactions between carhoxylate salts of ethanolamine, was confirmed by the appearance of an amide carbonyl peak at 1705 [cm.sup.-1].