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(organic chemistry)
The preparation of amines.
A process in which the amino group (=NH2) is introduced into organic molecules.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a method of introducting the amino group NH2 into various organic compounds. A typical example of amination is the action of alkali metal amides on heterocyclic bases. Thus, the interaction of pyridine with sodium amide at temperatures of about 200°C leads to the formation of α-aminopyridine (A. E. Chichibabin and O. A. Zeide, 1914):

C5H5N + NaNH2 → C5H4N(NH2) + NaH

Passing benzene vapor with ammonia through an incandescent tube results in a very low output of aniline:

C6H6 + NH3 → C6H5NH2 + H2

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Liang et al., "Chemical amination of graphene oxides and their extraordinary properties in the detection of lead ions," Nanoscale, vol.
Glycan derivatization includes reductive amination, Michael addition, hydrazide/alkoxy amino labeling, and (per)methylation/pertrimethylsilylation [12-14].
AaAaAeA{AaAaAeA We receive 500 patients day; they are offered a medical ex- amination, their needed x-rays, and the medication they shall use; all for a total of LE 35, which is almost for free,AaAaAeA{AaAaAeAo Shehab says.
Karim, "Palladium(0)-catalyzed amination of allylic natural terpenic functionalized olefins," Central European Journal of Chemistry, vol.
Sodium cyanoborohydride (Aldrich, Sweden), was used for reductive amination. Disposable PD-10 columns with Sephadex G-25 (GE Healthcare, UK) were used for separation and purification.
To design A2, both a-helical structure and C-terminal amination were considered because of its optimal amphipathic characteristics that increase its net positive charge and stability.
The company specializes in a wide range of organic reaction technologies such as Amination, condensation, hydrogenation; Amidation, dehydrogenation & Mannich Reaction; Alkylation, diazotization & nitration; Bromination, esterifiction & oxidation; Catalytic hydrogenation, etherification & reduction; Chlorination & hydrogenation.
Amination of naphthalene sulphate with R-NH2 (R = methyl, ethyl, n-propyl, iso-propyl, n-butyl, cyclohexyl) in the presence of sodium amide was reported by Kenichi and co- workers [4].
The emphasis of the research is on addressing fundamental challenges such as the use of carbon dioxide (C02) as a synthesis building block or more efficient amination reactions.
A family of new chiral C2 symmetric amido-oxazolinate ligands, bridged by three different linkers, have been synthesized via a modular Buchwald-Hartwig amination reaction.
Criteria for inclusion was as follows; patients with non infected closed mandibular angle fractures, which were displaced on clinical ex- amination and panoramic radiographs.