amino terminal


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amino terminal

[ə¦mē·nō ¦tərm·ən·əl]
(biochemistry)
The end part of a polypeptide chain which contains a free alpha-amino group.
References in periodicals archive ?
WT1 down regulates the EGFR6, PAX 2 and IGF-2.7 The addition of 68 amino acid amino terminal portion has a slight effect on the transcription.8 In comparison with the shorter versions of amino terminal, it increases activation potential.9
Natriuretic peptides, namely, brain natriuretic peptide (BNP) and amino terminal pro BNP (NT-pro BNP), are biomarkers released from ventricles in response to myocardial wall stress in case of impaired myocardial function.
Most strategies focus on the M protein, a surface protein with a high changeable amino terminal and a conserved carboxyl terminal [5].
A recent multicenter study investigated the utility of measuring levels of free FAs compared with other available clinical tests (i.e., amino terminal pro-B-type natriuretic peptide, IMA, heart fatty acid binding protein, classical troponin T, and high-sensitive troponin I) [32] and found that free FA had the highest overall sensitivity (75%), specificity (72%), and negative predictive values (92%) for discriminating acute coronary syndrome from nonischemic chest pain in patients admitted to the emergency department.
Renal clearance of B-type natriuretic peptide and amino terminal pro-B-type natriuretic peptide a mechanistic study in hypertensive subjects.
The mature form of the hGH is created from its 217 amino acid precursor after removal of the signal peptide (26 amino terminal residues).
12-20 The SNP rs721917 replaces methionine (nucleotide sequence ATG) with threonine (ACG) at residue number 11 in the amino terminal domain of the mature protein.
Second generation immunoassays, called intact PTH analysis, have a system of two antibodies, one specifically for the carboxyl terminal portion and one for the amino terminal portion of the molecule.
Moreover the amino terminal tethered ligand sequence37S38L plays a major role in the activation of PAR-2 (Al- Ani et al.
Segun estudios bioinformaticos, las expansinas son codificadas por miembros de una familia multigenica, que constan de tres dominios conservados: un peptido senal en el extremo amino terminal, un dominio que se postula de union a polisacaridos (CBD; por las siglas en ingles) hacia el carboxilo terminal, y un dominio central parecido al de la familia de las 45 endoglucanasas (EG45) que contiene un motivo histidina-fenilalanina-aspartato (HFD) y varios residuos de cisteinas (C) que se cree funcionan en la actividad catalitica (Cosgrove et al., 2002).
The isoleucine (I) is present on the 10th position from N-terminal side of Nivulian-II, which is fully homologous with isoleucine of Maturase K, as it is present on the 10th position from amino terminal side (Figure 3(a)).