This antibody was classified as myositis-specific autoantibody and its corresponding antigen was reported to be a 50-kDa histidine transfer ribonucleic acid (tRNA) synthetase, a type of cytoplasmic aminoacyl-tRNA synthetase
[20.] Masayoshi Yamaguchi, Hidetoshi Oishi and Yasunobu Suketa, Zinc stimulation of bone protein synthesis in tissue culture: Activation of aminoacyl-tRNA synthetase
, Biochemical Pharmacology, 37 (21), 4075-4080 (1988).
The hypothesis of this specific rooting scenario has been supported by several other studies [134, 137], including a study of genetic distances between paralogous pairs of aminoacyl-tRNA synthetase
(aaRS) proteins .
Separately, a 3-chlorotyrosinecharged tRNA containing a CUs anticodon, was prepared by a combination of chemical synthesis and enzymatic ligation, followed by aminoacylation of 3-chlorotyrosine using an aminoacyl-tRNA synthetase
The enzyme that catalyzes this amino acid-RNA attachment is the aminoacyl-tRNA synthetase
Autoantibodies against aminoacyl-tRNA synthetase
: novel diagnostic marker for type 1 diabetes mellitus.
Cubist received the milestone payment for developing and transferring technology enabling Bristol-Myers Squibb to target specific aminoacyl-tRNA synthetase
The aminoacyl-tRNA synthetase
structure is the subject of ongoing research and analysis by molecular biologists.
Recent study results have suggested that Hcy-induced vascular damage could be a result of Hcy-thiolactone (HcyT), an Hcy-reactive product formed in several cell types as a result of editing reactions of some aminoacyl-tRNA synthetase
Root of the universal tree of life based on ancient aminoacyl-tRNA synthetase
11:30 INCORPORATION AND INTRACELLULAR MAPPING OF HIS-TAGGED p43/EMAP II WITHIN THE MULTIENZME AMINOACYL-tRNA SYNTHETASE
Reaction of anti-OJ autoantibodies with components of the multi-enzyme complex of aminoacyl-tRNA synthetases
in addition to isoleucyl-tRNA synthetase.