It is worth mentioning that the notable feature of this oxidant is that even amine such as a- methyl aminopyridine
(entry, 11) and flurene (entry, 12) were easily converted to corresponding carbonyl compounds with reasonable yields.
The ground-breaking nature of the project is:A) Develop light-driven region- and/or enantioselective catalytic reductions using well-defined cobalt coordination complexes with aminopyridine
ligands, initially developed for water reduction.
The compound from the aminopyridine
class, code named MMV390048, shows potent activity against multiple points in the malaria parasite's lifecycle.
34 g (10 mmol) of E-cinnamyl alcohol (C9H10O) (commercially avaible) and 2 mL of acetic anhydride (Ac2O) (25 mmol) were mixed in 30 mL of pyridine with 10 mg of dimethyl aminopyridine
MS Research, Hope and Promise will offer an update on current treatments - including Betaseron, Copolymer 1, Avonex, 4 Aminopyridine
and Oral Myelin - with Dr.
The materials for the synthesis of the catalyst, dimethyl aminopyridine
p-toluene sulfonate (DPTS): p-toluene sulfonic acid and dimethylaminopyridine were also purchased from Sigma-Aldrich.
8,440,703 (the '703 patent) entitled "Methods of Using Sustained Release Aminopyridine
Based on the reported chemical and biological importance of 4-aminoantipyrine and 2- aminopyridine
we report herein the synthesis, analgesic and antioxidant activities of 4-amino antipyrine and 2-aminopyridine
11/102,559 entitled "Method of Using Sustained Release Aminopyridine
[AP] and 3,4-diaminopyridine [DAP]) are potassium channel blockers shown to improve nerve conduction in experimentally demyelinated axons.