(redirected from Aminotransferases)
Also found in: Dictionary, Thesaurus, Medical.
Related to Aminotransferases: aspartate aminotransferase, Transaminases


One of a group of enzymes that catalyze the transfer of the amino group of an amino acid to a keto acid to form another amino acid. Also known as aminotransferase.



(also aminotransferase and aminopherase), an enzyme of the transferase group that catalyzes the transfer of an amino group (—NH2) from an α-amino acid to an α-keto acid. Transaminases are found in most animal and plant tissues and play an important part in nitrogen metabolism. The role of transaminase in the transamination process was discovered by the Soviet biochemists A. E. Braunshtein and M. G. Kritsman in 1937. The coenzyme in transaminase reactions is pyridoxal phosphate, the aldehyde group of which serves as intermediate acceptor of the amino group. The resulting pyridoxamine phosphate transfers the amino group to the ketone group of the acid undergoing amination. The reaction is reversible.


References in periodicals archive ?
Higher concentrations of alanine aminotransferase within the reference interval predict nonalcoholic fatty liver disease.
Also, short term CPAP therapy doesn't seem have beneficial effects on serum aminotransferase levels in patients of OSAS.
Conclusion: Mean serum alanine aminotransferase value in young healthy adults included in this study was 29.
Alanine aminotransferase kit {(International Federation of Clinical Chemistry (IFCC)} without pyridoxal phosphate activation.
3] NAFLD causes elevation of serum aminotransferases and liver disease, which could end up in fibrosis, cirrhosis, and eventually hepatic carcinoma.
10 mg/L], aspartate aminotransferase level 30 U/L (reference value 37 U/L), and alanine aminotransferase level 21 U/L (reference value 41 U/L).
The aminotransferases increased according to the number of CT findings and were log transformed for the parametric statistics (AST, P = 0.
Plasma enzyme activities of alanine aminotransferase and aspartate aminotransferase were determined using commercial kits (Zhongsheng Bio-Technology and Science Inc.
The levels of these parameters: glucose, triglycerides, albumin, globulin, total protein, cholesterol, aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, and [gamma]-glutamyltransferase in blood, liver and kidney were used.
Cypermethrin induced alterations that are both time dependent and tissue-specific with glutamate dehydrogenase (GDH) aspartate aminotransferase (ASAT) and alanine aminotransferase (ALAT) enzymes showing a significant elevation in all tissues after both lethal and sub-lethal exposure.
5 mg/dL CO2 31 mmol/L 18-27 mmol/L Aspartate aminotransferase 3669 U/L 15-40 U/L Alanine aminotransferase 676 U/L 27-42 U/L Alkaline phosphatase 150 U/L 92-336 U/L 7-Glutamyl transpeptidase 10 U/L 14-35 U/L
The secondary effects of the medication are usually mild; reports have been made of constipation, abdominal pain, nausea, drowsiness, dizziness, pruritus, transient hair loss, anorexia, and mild aminotransferase increase (3,5,7).