(redirected from Aminotransferases)
Also found in: Dictionary, Thesaurus, Medical.
Related to Aminotransferases: aspartate aminotransferase, Transaminases


One of a group of enzymes that catalyze the transfer of the amino group of an amino acid to a keto acid to form another amino acid. Also known as aminotransferase.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



(also aminotransferase and aminopherase), an enzyme of the transferase group that catalyzes the transfer of an amino group (—NH2) from an α-amino acid to an α-keto acid. Transaminases are found in most animal and plant tissues and play an important part in nitrogen metabolism. The role of transaminase in the transamination process was discovered by the Soviet biochemists A. E. Braunshtein and M. G. Kritsman in 1937. The coenzyme in transaminase reactions is pyridoxal phosphate, the aldehyde group of which serves as intermediate acceptor of the amino group. The resulting pyridoxamine phosphate transfers the amino group to the ketone group of the acid undergoing amination. The reaction is reversible.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The limitations of our study are, it's a cross sectional observational study, S ferritin and aminotransferases are measured only on the day of admission Thus, a relatively larger cohort study with follow ups would require to ascertain the findings of the present study.
(7) Nonspecific reactive hepatitis again includes a group of similar findings to the minor nonspecific changes often seen in biopsies from asymptomatic patients with elevated aminotransferases. However, the entity is separated from cases of residual hepatitis with prominent clusters of debris-laden macrophages indicating recent hepatic necrosis.
High prevalence of nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus and normal plasma aminotransferase levels.
Relative elevations of serum alanine and aspartate aminotransferase in muscular dystrophy.
Aminotransferases. In the present patient population, only 30% of patients attending CILM had aminotransferases records.
Although aminotransferases are widely applied in the clinic as sensitive biomarkers for hepatocyte injury, the concurrence of increased serum CK and aminotransferases is indicative for muscle injury in most cases in dystrophinopathy [20, 42, 43].
All of the patients had aminotransferases in the normal range before treatment.
Also, short term CPAP therapy doesn't seem have beneficial effects on serum aminotransferase levels in patients of OSAS.
Though diagnosis with biopsy is the gold standard, HSV PCR with concurrent elevation in aminotransferases can serve as substitute markers for making the diagnosis.
Conclusion: Mean serum alanine aminotransferase value in young healthy adults included in this study was 29.9 8 IU/L which is lower than normal reference provided at present which is 40 IU/l.
[1] Serum aminotransferases are not highly increased in this disorder.
In chicks, transaminases are sensitive and specific indicators for vitamin [B.sub.6] status and vitamin [B.sub.6] deficiency significantly reduces the activities of aspartate aminotransferase and alanine aminotransferase in blood (Cheney et al., 1965; Yen et al., 1976; Oloyo, 2001), but its indicator status has not been reported in ducks.