amphotericin B

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amphotericin B

(ăm'fətĕr`ĭsĭn), antibioticantibiotic,
any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms. Types of Antibiotics
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 that halts the growth of several disease-causing fungi. Discovered in 1956, it is produced by bacteria of the genus Streptomyces. It is used in lotion or ointment form to treat fungal infections of the skin and is given internally only to patients with potentially fatal fungal infections. Amphotericin B is not effective against bacterial infections.

amphotericin B

[‚am·fə′ter·ə·sən ′bē]
(microbiology)
C46H73O20N The active component of amphotericin, suitable for systemic therapy of deep or superficial mycotic infections.
References in periodicals archive ?
In Case 1, the patient received relatively complex treatment, which included empirical monotherapy (caspofungin), empirical combination therapy (caspofungin plus amphotec), targeted combination therapy (voriconazole [minimum inhibitory concentration-90 (MIC-90) of 0.25 [micro]g/ml] plus amphotec [MIC-90 of 1 [micro]g/ml]), maintenance and consolidation therapy (voriconazole).
Known by the trade names Abelcet, Ambisome, and Amphotec are lipid formulations of amphotericin B.
Three different lipid preparations of amphotericin B are now commercially available: Abelcet, AmBisome, and Amphotec. There's no question that the liposomal preparations are less nephrotoxic, generally safer, and better tolerated than conventional amphotericin B, Dr.