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Related to Amyloid precursor protein: amyloidosis, Tau protein

app

app

(1) (APPlication) The file extension for executable Mac applications. See APP file.

(2) (APPlication) The term has been shorthand for "application" in the IT community for a long time. However, it became popular with the consumer for mobile applications in smartphones and tablets after Apple debuted the iPhone 3G in 2008. It is just as correct to say "iPhone application" as it is "desktop computer app;" although app is shorter, and computer people love to abbreviate. See application and online app store.

(3) (APPlication) In the engineering world, an app can refer to a circuit design, using the word "application" in the context of purpose. For example, "high-voltage apps" means high-voltage circuit designs. The term predates mobile software apps by decades.


Apps Are Everywhere
After installing a new smart TV, as in this Samsung 4K TV example in 2016, users have the option of downloading apps from Netflix, Amazon and other content providers.







And We Do Mean "Everywhere"
For decades the word "apps" have been shorthand for "appetizers" and it still is.
References in periodicals archive ?
In FAD the cause of the disease is a genetic mutation in the genes coding for the amyloid precursor protein (APP), presenilin-1 (PS1) or presenilin-2 (PS2) (47).
The mother protein is amyloid precursor protein, or APP.
Finally, three end products are formed (sAPP-[beta], A[beta], and amyloid precursor protein intracellular domain, AICD).
In murine model, it has been shown that the host protein Amyloid-a protein is composed of 40 to 43 amino acids which is generated from amyloid precursor protein (APP), by the proteolytic cleavage, which is a ubiquitous transmembrane protein involved various cellular processes such as neuronal protein trafficking along the axon, neurite outgrowth and synaptogenesis, transmembrane signal transduction, Ca2+ signaling and cell adhesion (20,21).
The scientists, from the University of Cambridge, found that as a protein called amyloid precursor protein (APP) is broken down into toxic protein fragments called amyloid-beta, it affects changes in the way that another key protein, tau, behaves.
The two major hallmarks of AD pathology, Abeta plaque deposition and neurofibrillary tangles, arise from increased proteolytic processing of the amyloid precursor protein (APP) and microtubule destabilization due to tau hyperphosphorylation, respectively.
Amongthe clumpy proteins Buhimschi and her colleagues discovered in the urine was amyloid precursor protein, or APP, a protein that, when cleaved into fragments, forms plaques in the brains of people with Alzheimer's.
The collaboration will initially involve the co-development and commercialization of Eisai's two candidates: E2609, a [beta]-site amyloid precursor protein cleaving enzyme (BACE) inhibitor, and BAN2401, an anti-A[beta] antibody.
The purpose of this study was to investigate whether repeated electroacupuncture (EA) stimulation would improve cognitive function and the pathological features of AD in amyloid precursor protein (APP)/presenilin 1 (PS1) double transgenic mice.
A first step to accumulating beta amyloid is the production of amyloid precursor protein (APP).
The study revealed that loss of NEU1 activity was linked with a build-up in lysosomes of the amyloid precursor protein (APP) that they identified as a natural target of the enzyme.
1) Prolonged cerebral hypoxia increases amyloid precursor protein production and [beta]-secretase activity.