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Related to Amyloid precursor protein: amyloidosis, Tau protein


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(1) (APPlication) The file extension for executable Mac applications. See APP file.

(2) (APPlication) The term has been shorthand for "application" in the IT community for a long time. However, it became popular with the consumer for mobile applications after Apple debuted the iPhone in 2008. Application and app are synonymous, and it is just as correct to say "iPhone application" as it is "desktop computer app." App is shorter, and computer people love to abbreviate (see TLA). See application and online app store.

(3) (APPlication) In the engineering world, an app can refer to a circuit design, using the word "application" in the context of purpose. For example, "high-voltage apps" means high-voltage circuit designs. The term predates mobile software apps by decades.

Apps Are Everywhere
After installing a new smart TV, as in this Samsung 4K TV example in 2016, users have the option of downloading apps from Netflix, Amazon and other content providers.

We Do Mean "Everywhere"
For decades the word "apps" has been shorthand for "appetizers" and still is.
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References in periodicals archive ?
BACE is a key enzyme in the production of Abeta peptides, which inhibits beta site of amyloid precursor protein (APP).
[beta]-secretase is a protease that acts in place of amino acid, aspartic acid and produces [beta]-amyloid peptide and the C99 fragment, the 99 amino acids from the C-terminal of the amyloid precursor protein. Next, y-secretase cleaves amyloid precursor protein and produces p-amyloid peptides with different sizes, [alpha]-secretase with the effect on the amyloid precursor protein produces C83 fragment.
MicroRNA-135a and -200b, potential biomarkers for Alzheimer's disease, regulate [sz] secretase and amyloid precursor protein. Brain Res 2014;1583:55-64.
Hassan, "Amyloid precursor protein promotes postdevelopmental neurite arborization in the Drosophila brain," The EMBO Journal, vol.
Familial Alzheimer's disease is attributable to mutations in the sequences for the genes encoding the amyloid precursor protein (APP) or its processing enzymes (Selkoe, 1996).
Amyloid precursor protein (APP) severing disorder lead to over expression or less clearance of A[beta], and then A[beta] became aggregated.
In a previous study, we found that DSCAM was also overexpressed in the cortex of the amyloid precursor protein (APP) transgenic mouse model of AD (2).
Subsequently, cDNA cloning was performed and amyloid precursor protein (APP) was discovered in 1986-1987.
Neurons in this model have both amyloid precursor protein (APP) and presenilin 1 mutations and thus showed significant increases in the ratio of pathogenic A[beta]42 to A[beta]40 peptides compared with non-AD control neurons [2,11].
This hydrophobic polypeptide is proteolytically produced by [beta]- and [gamma]-secretases from a single transmembrane polypeptide referred to as amyloid precursor protein (APP) (Zhou et al., 2011).
Molecular mechanism of Amyloid Precursor Protein (APP) processing
One thing that scientists on both sides of the beta-amyloid debate have noticed is that beta-amyloid has what amounts to a sister protein: amyloid precursor protein intra cellular domain, or AICD.