Topical products containing Anacyclus pyrethrum extracts are already commercially available with functional, cosmeceutical claims.
Both purified pellitorine, as well as the ethanolic extract of Anacyclus pyrethrum were used in this study to investigate if there was a difference in penetration of pellitorine through human skin, as co-compounds in the plant extract could influence the skin penetration as well.
Analytical characterisation of the Anacyclus pyrethrum extract
The Anacyclus pyrethrum root extract was prepared as previously described (Boonen et al., 2012a).
Pellitorine was isolated and purified from the Anacyclus pyrethrum extract by means of semi-preparative HPLC as follows.
Dose solutions of the Anacyclus pyrethrum extract and the purified pellitorine were prepared in 30:70 [H.sub.2]O:EtOH (V/V).
Roots powder of Anacyclus pyrethrum is well known as sternutatory, sudorific and anti infectious (Doudach et al., 2012).
Phytochemical study was achieved only with Anacyclus pyrethrum L.
Anacyclus Pyrethrum EO from Algeria is dominated by germacrene-D and defined by the germacrene-D chemotype (Selles, 2012; Selles et al, 2013).
Anacyclus pyrethrum therefore appears to be a plant rich in secondary metabolites.
Centre for Mediterranean Cooperation, International Union for Conservation of Nature and Natural Resources: Anacyclus pyrethrum L.
clavatus (Desf.) Pers., T, Med, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18.