ACE inhibitor

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Related to Angiotensin converting enzyme inhibitors: Angiotensin receptor blocker, Beta blockers, Losartan, Calcium channel blockers

ACE inhibitor

ACE inhibitor (āˌsēˌēˈ, ās) or angiotensin-converting enzyme inhibitor (ănˌjēōtĕnˈsĭn), drug used to reduce elevated blood pressure (see hypertension), to treat congestive heart failure, and to alleviate strain on hearts damaged as a result of a heart attack (see infarction). ACE inhibitors block production of an enzyme that helps convert the protein angiotensin 1 into angiotensin 2, a protein that makes blood vessels constrict and promotes retention of fluid, raising blood pressure. Thus ACE inhibitors act to widen the blood vessels and make it easier for the heart to pump blood through the body. captopril (Capoten), ramipril (Altace), and enalapril (Vasotec) are commonly used ACE inhibitors. Angiotensin-receptor blockers (ARBs), such as losartan (Cozaar) and valsartan (Diovan), reduce hypertension by displacing angiotensin 2 from receptors on the surface of cells. ARBs are used as alternatives to the less expensive ACE inhibitors because they have fewer side effects.
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References in periodicals archive ?
KEY WORDS: Angiotensin converting enzyme inhibitor, Glomerular hyperfiltration, Type 1 diabetes.
Angiotensin Converting Enzyme Inhibitors, Angiotensin Receptor Blockers.
Among specific topics are anti-glaucoma carbonic anhydrase inhibitors as opthalmologic drugs, crystallographic studies of carbonic anydrases from fungal pathogens for structure-assisted drug development, sulfonylated matrix metalloproteinase inhibitors, Clostridium histolyticum collagenase inhibitors in the drug design, angiotensin converting enzyme inhibitors, and inhibitors of histidinol dehydrogenases as antibacterial agents.
Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists for preventing the progression of diabetic kidney disease.
(Mercaptopropanoyl) indoline-2-carboxylic acids and related compounds as potent angiotensin converting enzyme inhibitors and antihypertensive agents.
* Angiotensin converting enzyme inhibitors. ACE inhibitors keep the body from making angiotensin II, a hormone that normally causes blood vessels to narrow.
and angiotensin converting enzyme inhibitors or aldosterone receptor blockers.
Angiotensin converting enzyme inhibitors (ACEIs) such as captopril (Capoten) and enalapril (Vasotec) may be used to prevent urinary protein losses that are associated with diabetes damage to the kidney.

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