Cystatin has also been identified from the cystatin superfamily which encompasses proteins that contain multiple cystatin-like sequences and is considered to be a tumoral marker gastrointestinal esophageal squamous cell carcinoma (56), and colorectal cancer; (57) ankyrin-3 other protein found in tears, is an immunologically dis tinct gene product from ankyrins
ANK1 and ANK2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems.
Ankyrins. In our prediction list, two of the candidate genes, ANK1 and ANK2, turned out to be the functional members of the ankyrins.
Susuki et al., "Paranodal ankyrins: enigmatic glial anchors?" Journal of Neurochemistry, vol.
Ankyrins: adaptors between diverse plasma membrane proteins and the cytoplasm.
 Ankyrin G (ANKG), which is encoded by the ANK3 gene, is crucial for the stability of the neuronal membrane [5, 6] and facilitates the connection between axons and ribbon synapses.
The ANK1 gene encodes Ankyrins
, which are a family of proteins that link membrane proteins to the cytoskeleton (Chorzalska et al., 2010), and the APBB1IP gene functions in signal transduction from Ras activation to cytoskeleton remodeling (Inagaki et al., 2003).
Ankyrins also play critical roles for ion channel regulation in other excitable cells, such as neurons and heart cells called cardiomyocytes,"
The new mechanism involves a protein called ankyrin and appears to regulate specialized pancreatic cells and insulin secretion
There are indications that mechanisms underpinning host-microbe interactions are encoded on the genome of "Candidatus Poribacteria WGA A3." These are proteins with eukaryote-like domains, such as ankyrin
repeats and tetratricopeptide repeats (TPR), which are likely to mediate protein-protein interactions (Siegl et al., 2011).