In solution, glucose may exist as one of two possible anomers
, termed [alpha] and [beta], or as the open-chain glucose aldehyde.
It was observed that during per acetylation, a mixture of both [alpha] and [beta] anomers
is formed in a 3:1 ratio.
The weak bands observed near 926 [cm.sup.-1] and 760 [cm.sup.-1] are [alpha] anomers
of pyranose compounds.
Inhibition of gastric motility induced by hepatic portal injections of D-glucose and its anomers
. J Physiol 1984; 351: 573-581, doi: 10.1113/ jphysiol.1984.sp015263.
Cahill Jr., "Pancreatic beta cell toxicity by streptozotocin anomers
," Diabetes, vol.
Meanwhile, lectins have unique ability to distinguish subtle structural differences among saccharides, e.g., epimers, anomers
, and linkage isomers, etc.
Since the anomeric hydroxyl group of the glucose moiety of 6 is unacylated, it may be obtained as anomers
([alpha]- and [beta]-forms) mixture.
Figure 4 illustrates the separation of saccharides at high pH, with 0.1% ammonia, and high temperature to prevent double chromatographic peaks due to the formation of anomers
. In this type of application, PGC also is stable under high temperature and high pH.
Glucose undergoes mutarotation between its different anomers
. It is postulated that the glucose a-anomers bind faster than the [beta\-anomers, but the overall response is poor because the relative abundance of [alpha]-anomers is low and interconversion between the different diastereoisomers is slow.