Antabuse


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Antabuse

(ăn`təbyo͞os), trade name for the drug tetraethylthiuram disulfide, used in the treatment of alcoholismalcoholism,
disease characterized by impaired control over the consumption of alcoholic beverages. Alcoholism is a serious problem worldwide; in the United States the wide availability of alcoholic beverages makes alcohol the most accessible drug, and alcoholism is the most
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. Also called sulfiram, Antabuse is nontoxic, but it alters the metabolism of alcohol in the body, making it impossible for one who is taking the drug to drink without experiencing severe discomfort. When alcohol is present the drug increases the concentration of acetaldehyde in the body, causing symptoms resembling those of a bad hangover: the individual feels hot, the face becomes flushed, the neck and head throb, and nausea, vomiting, and headache may follow. Small quantities of alcohol, such as from food sauces and cough medicines, and even inhaled traces from shaving lotions and varnishes, may induce the same symptoms. The drug Temposil, or citrated calcium carbamide, has the same function as Antabuse, but is weaker and safer. The therapeutic use of Antabuse was discovered in the 1930s when workers exposed to tetraethylthiuram disulfide, a chemical used in the rubber industry, became ill after drinking alcoholic beverages.
References in periodicals archive ?
Death following "Test Drink" of alcohol in patients receiving Antabuse.
ii) She also attends Dr C, where the giving of periodic blood tests and the taking of Antabuse [a drug prescribed to recovering alcoholics to help them abstain from drinking alcohol] are vital ingredients to prevent her returning to alcohol.
Andrew is now on Antabuse - the same drug George Best uses for his alcoholism - and has been teetotal for eight months.
The Providence Summit was sponsored through an educational grant from primary sponsor Odyssey Pharmaceuticals, manufacturer of Antabuse, a federally approved medication to treat alcoholism.
Brewer, Controlled Trials of Antabuse in Alcoholism: The Importance of Supervision and Adequate Dosage, 86 ACTA PSYCHIATRICA SCANDINAVICA SUPPLEMENTUM 51, 51-55 (1992) (demonstrating the importance of close supervision to the successful use of Antabuse).
dizziness, antabuse reactions (alcohol content), hyperlipidemia, hyperglycemia, lipodystrophy, hepatitis indinavir (IDV) Kidney stones, GI Take 2 capsules/dose (Crixivan[R]) (nausea, diarrhea, q 8h on an empty vomiting, abdominal stomach (1 hr before pain); neurologic: or 2 hours after a headaches, insomnia, meal) or with a light change in taste, dry meal (skim milk, skin, hair loss, juice, coffee, tea, hyperlipidemia, dry toast, corn hyperglycemia, flakes).
He had Antabuse tablets inserted into his stomach to keep him on the wagon after being warned that just one more drink could kill him.
He cut out alcohol and had Antabuse tablets inserted into his stomach to keep him on the wagon after he was warned just one more drink could kill him.
Over the years she tried a number of tricks to limit Bishop's drinking, such as hiring a housekeeper to keep an eye on things and empty hidden bottles of alcohol, and getting a prescription for Antabuse, which she sometimes persuaded Bishop to ingest.
They said a new treatment was needed because other medications, such as Antabuse, sometimes cause nausea and headaches.
Now he takes 12 pills a day and has Antabuse implants in his stomach which make him violently ill if he touches a drop of alcohol.