Anthelmintic


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

anthelmintic

[¦an·thel¦min·tik]
(pharmacology)

Anthelmintic

 

(also vermifuge, helminthagogue), a preparation used to treat worm diseases, or helminthiases. The action of different anthelmintics varies. Some preparations, such as Heptylresorcine and Phenasal, damage the cuticle (integument) of helminths, while other preparations, such as santonin, ditrazin, piperazine, and naphtammone, alter the tone and mobility of parasites. Anthelmintics expel helminths from the patient’s body and are used when helminths infest the intestine and its communicating organs (liver, pancreas). Anthelmintics are also used to kill helminths.

Piperazine acts on the neuromuscular system of ascarids, which are subsequently excreted with feces. Phenasal destroys the integument of various tapeworms, including beef tapeworms, dwarf tapeworms, and broad tapeworms. They are then digested in the intestine and their residue is excreted. Chloxyl kills Siberian liver fluke in the liver and pancreas. The parasite is then eliminated into the intestine. Other anthelmintics, such as ditrazin and antimony preparations, destroy helminths, such as filiariae and schistosomes, in the blood, lymphatics, and tissues. Some antihelmintics, such as ditrazin and Chloxyl, are produced chemically. Others are obtained from plants, for example, from Artemisia cina or the extract of male fern.

REFERENCE

Krotov, A. I. Osnovy eksperimental’noi terapii gel’mintozov. Moscow, 1973.

N. N. PLOTNIKOV

References in periodicals archive ?
Effects of three anthelmintic treatment regimes against Fasciola and nematodes on the performance of ewes and lambs on pasture in the highlands of Kenya.
Resistance to anthelmintics is a real concern for the Welsh sheep industry, with reports of resistance to the 3-ML group now commonplace.
Anthelmintic efficacy against cyathostomins in horses in Southern England.
The results indicated that plant has secondary metabolites that have broad anthelmintic properties and plant might be a novel source of pharmaceutical drugs against helminthes.
Anthelmintic assay shows that ethyl acetate extract at 20,000ppm has the least time to paralyze and kill the test organisms, 1.
Treatment with anthelmintic agents and systemic steroids hasten recovery of ocular symptoms and funduscopic findings, and prevent irreversible vision loss and recurrence.
Gastrointestinal (nematode) infections in small ruminants: Epidemiology, anthelmintic efficacy and the effect of wattle tannins.
Anti-coccidial, anthelmintic and antioxidant activities of pomegranate (Punica granatum) peel extract.
Anthelmintic resistance in cattle nematode in the western Pampeana Region of Argentina.
giganticaadult fluke after 24h incubation with different doses of ethanolic extracts of Calligonum comosum plant concerned, had provided evidence for the greater anthelmintic activity of C.