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Related to Anthelmintic drug: Antihelminthic Drugs





(also vermifuge, helminthagogue), a preparation used to treat worm diseases, or helminthiases. The action of different anthelmintics varies. Some preparations, such as Heptylresorcine and Phenasal, damage the cuticle (integument) of helminths, while other preparations, such as santonin, ditrazin, piperazine, and naphtammone, alter the tone and mobility of parasites. Anthelmintics expel helminths from the patient’s body and are used when helminths infest the intestine and its communicating organs (liver, pancreas). Anthelmintics are also used to kill helminths.

Piperazine acts on the neuromuscular system of ascarids, which are subsequently excreted with feces. Phenasal destroys the integument of various tapeworms, including beef tapeworms, dwarf tapeworms, and broad tapeworms. They are then digested in the intestine and their residue is excreted. Chloxyl kills Siberian liver fluke in the liver and pancreas. The parasite is then eliminated into the intestine. Other anthelmintics, such as ditrazin and antimony preparations, destroy helminths, such as filiariae and schistosomes, in the blood, lymphatics, and tissues. Some antihelmintics, such as ditrazin and Chloxyl, are produced chemically. Others are obtained from plants, for example, from Artemisia cina or the extract of male fern.


Krotov, A. I. Osnovy eksperimental’noi terapii gel’mintozov. Moscow, 1973.


References in periodicals archive ?
These authors, from India, set out to evaluate the effect of routine administration of intestinal anthelmintic drugs on haemoglobin by making a systematic review of randomised controlled trials.
The DOH had targeted to administer the anthelmintic drugs albendazole and mebendazole to about 848,947 children aged 5 to 18 in the Zamboanga provinces and this city.
As the percentage of the worms is high in children of IDPs, parents need to be encouraged to consult physicians for giving their children proper dosage of anthelmintic drugs.
The project by Aberystwyth University's IBERS unit has been given impetus by the growing levels of resistance to existing anthelmintic drugs and the lack of suitable vaccines.
FARMERS and vets in the North East have the opportunity to find out more about the UK livestock industry's increasing problem of roundworms which show resistance to anthelmintic drugs.
WITH roundworms in sheep showing increasing resistance to anthelmintic drugs, a free meeting designed to help farmers achieve more effective control of the parasites takes place at Castle of Brecon Hotel, Brecon, tomorrow.
Anthelmintic drugs have a broad spectrum of activity.
Next to antibiotics, administering anthelmintic drugs is often a farmer's second highest production cost, Fetterer says.
Where both ascarids and hookworms are commonly transmitted, anthelmintic drugs should be given to pups at ages 2, 4, 6, and 8 weeks of age.
It was reported that the administration of intestinal anthelmintic drugs could induce severe effects to the host (Gulani et al.