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McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



(also vermifuge, helminthagogue), a preparation used to treat worm diseases, or helminthiases. The action of different anthelmintics varies. Some preparations, such as Heptylresorcine and Phenasal, damage the cuticle (integument) of helminths, while other preparations, such as santonin, ditrazin, piperazine, and naphtammone, alter the tone and mobility of parasites. Anthelmintics expel helminths from the patient’s body and are used when helminths infest the intestine and its communicating organs (liver, pancreas). Anthelmintics are also used to kill helminths.

Piperazine acts on the neuromuscular system of ascarids, which are subsequently excreted with feces. Phenasal destroys the integument of various tapeworms, including beef tapeworms, dwarf tapeworms, and broad tapeworms. They are then digested in the intestine and their residue is excreted. Chloxyl kills Siberian liver fluke in the liver and pancreas. The parasite is then eliminated into the intestine. Other anthelmintics, such as ditrazin and antimony preparations, destroy helminths, such as filiariae and schistosomes, in the blood, lymphatics, and tissues. Some antihelmintics, such as ditrazin and Chloxyl, are produced chemically. Others are obtained from plants, for example, from Artemisia cina or the extract of male fern.


Krotov, A. I. Osnovy eksperimental’noi terapii gel’mintozov. Moscow, 1973.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Considering the multifaceted socioeconomic consequences of zoonotic helminth infections and increasing rates of anthelmintic drug resistance, a quest to new alternative control strategies, like probiotics, is urgently needed to mitigate infection.
This difference in reduced efficacy in this study area may be due to drug usage strategies, biology of the parasite, and the quality of the available anthelmintic drugs.
As the percentage of the worms is high in children of IDPs, parents need to be encouraged to consult physicians for giving their children proper dosage of anthelmintic drugs. Moreover, proper hand-washing after defecation, availability of clean drinking water and good environmental hygiene are also required.
The use of anthelmintic drugs for therapy of neurocysticercosis results in better resolution of viable parenchymal cysts and lower risk of recurrence, and reduces seizure frequency when compared with placebo.
Choose from a great variety of anthelmintic drugs that are safe and effective against ascarids, hookworms, and other intestinal helminths of dogs and cats (Table 1).13 The drugs are available in tablet, granule, liquid, and other formulations whose manufacturers recommend single or multiple daily doses and periodic or continuous administration.
Effect of administration of intestinal anthelmintic drugs on haemoglobin: systematic review of randomized controlled trials.
Control and Treatment: Usually equines are treated with anthelmintic drugs to eliminate adult strongyles from the large intestines to prevent excessive contamination of pastures with eggs and L3s.
Sheep was not treated with any anthelmintic drugs as no specific therapeutic strategies have been outlined for non cerebral coenurosis (Oryan et al., 2014) and animal recovered after surgical excision of cyst and post operative treatment with antibiotics.
The results of these studies suggest that TPP could be a good target for new anthelmintic drugs. Promising results were obtained by Kushwaha et al.
The ability to grow all of the life stages of a digenean in vitro would benefit development of anthelmintic drugs and vaccines [1] and facilitate research into the ecology, evolution, genetics, and behavior of these parasites [2-5].
Mass treatment of sheep and cattle with TCBZ (Fasinex) or in combination with other anthelmintic drugs is common in the Netherlands (L.