The results from a 10-year randomized trial known as the CABANA trial (Catheter Ablation versus Antiarrhythmic Drug
trial for Atrial Fibrillation) have recently been released.
No cardiac injury was determined, and the rhythm reverted to normal sinus rhythm spontaneously on the 3rd hour after the accident without the use of any antiarrhythmic drug
Findings during electrophysiology testing Finding Atrial flutter Sinus rhythm P value group (n = 94) group (n = 94) Spontaneous atrial 2 (2.1%) 4 (4.3%) 0.68 fibrillation Inducible atrial 7 (7.5%) 20 (21.3%) 0.007 fibrillation Atrial fibrillation 5 (71.4%) 8 (40%) 0.15 requiring cardioversion Median flutter cycle 258 (180-370) 252.5 (183-370) 0.34 length (range), ms Bidirectional block 93 (98.9%) 94 (100%) NA Isthmus dependent 85 (95.5%) 63 (90%) 0.29 Antiarrhythmic drugs
20 (21.3%) 15 (15.9%) 0.35 prescribed at discharge
Also, other antiarrhythmic drugs
were not available in Turkey.
Propafenone (Rythmol, Abbott, Chicago, IL, USA) is a group 1C antiarrhythmic drug
that has sodium channel-blocking effects.
Multiple clinical trials have established the superiority of CA over antiarrhythmic drug
therapy (AAD) for the maintenance of sinus rhythm and improvement of quality of life.
Treatment options for arrhythmic syncope include implantable cardiac pacemakers, defibrillators, antiarrhythmic drugs
and catheter ablation.
Brugada syndrome is diagnosed in patients with Type 2 or Type 3 ST-segment elevation in [greater than or equal to]1 lead among the right precordial leads V1,V2 positioned in the 2nd, 3rd, or 4th intercostal space when a provocative drug test with intravenous administration of Class I antiarrhythmic drugs
induces a Type 1 EKG morphology.
We then summarized the recent advances on the pharmacological effects of natural antiarrhythmic drugs
in treating cardiac arrhythmia, exploring their potential mechanisms, and looking for novel targets.
* Be sure to take antiarrhythmic drugs
(if applicable) and blood thinners exactly as prescribed.
Lightheadedness was more common in women taking antiarrhythmic drugs
than in those not taking the drugs.