Titer

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titer

[′tī·tər]
(chemistry)
The concentration in a solution of a dissolved substance as shown by titration.
The least amount or volume needed to give a desired result in titration.
The solidification point of hydrolyzed fatty acids.
(textiles)
The weight per unit length of yarn.
The number of filaments in reeled silk thread.

Titer

 

(in analytical chemistry), the concentration of a solution expressed as the amount (in grams) of a substance dissolved in 1 milliliter (ml) of solution or as the amount of any substance that reacts with 1 ml of the given solution. Accordingly, a distinction is made between the titer for a dissolved substance (for example, the titer of the solution of hydrochloric acid, THCI) and the titer for a substance to be determined (for example, the titer of the solution of hydrochloric acid for sodium hydroxide, THCI/NaOH). The titer is calculated from the formula T = P/V, where T is the titer of the solution in g/ml, P is the weight of the batch in g, and V is the volume of the measuring flask in ml. Solutions with a known titer, called standard solutions, are used in titrimetric analysis.


Titer

 

in immunochemical analysis, the maximum or optimum dilution of antigens, antibodies, or complement at which a positive reaction between antigens and antibodies can be recorded or the reaction of one or both components can be registered against a standard. In some cases, such as complement fixation, the maximum antigen concentration at which sensitized erythrocytes can still be lysed is taken as the antigen titer. Determination of the titer is useful in making a quick estimate of the activity of immune serums.

Three kinds of titration are used in immunochemical analysis. In one method, pipettes are used to add different amounts of the material being titrated to identical volumes of the solvent or for successive transfer of a mixture of the material and solvent to test tubes containing an identical quantity of solvent; in the latter case, equal volumes of the material, solvent, and mixture to be transferred are usually taken, which produces twofold dilutions. The second method is similar, except that capillary tubes are used and the volumes are measured from the number of drops. Glass loops capable of holding strictly standard volumes of liquid are used in automatic titration.

N. A. DORFMAN


Titer

 

(titre), in the textile industry, a number used to rate the thickness of fibers and yarns (chiefly silk). The titer is expressed as the product of the cross-sectional area of a fiber or yarn and the density of its material (or as the ratio of the weight of a fiber or yarn to the length). The titer came into use in the 18th century. A unit known as a legal titer has been used since 1900; it is numerically equivalent to the weight in grams of a yarn 9 km in length. In the USSR the tex replaced the titer in 1956.

References in periodicals archive ?
However, the homozygotes of the resistant allele A were found to present the lowest HI antibody titer to AIV after boosting vaccination, indicating the negative effects of the resistant allele A for the fitness of chicken to AIV, even if positive selection on this gene has been observed (Li et al., 2006; Hou et al., 2007, Berlin et al., 2008).
The above phenomenon was very noticeable in the case of antibody titer and WBC counts.
Samples were considered positive if three immunohistochemical criteria were fulfilled.[2] Antibody titers were measured with enzyme-linked immunosorbent assay on HEK293 cell lysates ectopically expressing NR1 or NR1-NR2B heteromers.[2]
O-AIV vaccine induced 39.4, 128 and 128 units of geometric mean anti-AIV-HI antibody titers in the vaccinated broilers on 21, 28 and 35 DPV, respectively.
Among 50 goats examined 2 gave an antibody titer of 1: 16 which indicated residual or nonspecific immunity; one showed antibody titer of 1:128 which is due to acquired or evolving immunity whereas no goat was positive at antibody titer of 1:256 which suggests absence of recent contact with parasite.
Group F shows the highest HI antibody titer (294.1) which was vaccinated with ND only.The lowest HI antibody titer was recorded in group E (32.0).
First, although higher postvaccination antibody levels generally are associated with greater protection from influenza-like illness and its complications (2-4), there is no absolute antibody titer that ensures protection.
There were no statistically significant relationships between peak antibody titer and the subject's sex or delayed hypersensitivity response to an intradermal Candida challenge.
In addition, the higher antibody titers for persons who had ticks bites in the past year indicate a correlation between tick bites and antibody titer positivity.
A positive antibody titer means that your cat's immune system is producing antibodies to a pathogen, and if enough antibody is produced, this may provide protection from infection.
The second group included anaplasmosis patients defined by [greater than or equal to] 1 if the following criteria: intraleukocyte morulae on blood smears, a positive PCR result for Anaplasma, a 4-fold increased antibody titer for A.

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