However, oxybutynin is the only anticholinergic agent
for overactive bladder that can be administered as a transdermal patch.
There are currently 5 anticholinergic agents
approved by the US Food and Drug Administration (FDA) for the treatment of overactive bladder (OAB): oxybutynin, toherodine, trospium, solifenacin, and, most recently, darifenacin.
Responses to crude brevetoxins alone were compared with the responses obtained after treating the animals with the histamine [H.sub.1]-antagonist diphenhydramine, the anticholinergic agent
atropine, the glucocorticosteroid budesonide, or the bradykinin [B.sub.2] receptor antagonist HOE-140.
However, other anticholinergic agents
such as atropine have been used in the past to achieve the desired pulmonary effect.
* For reliever therapy, the primary bronchodilators are the short-acting beta-agonists (SABA), although anticholinergic agents
may be suitable for older adults, for those intolerant of SABA, and for patients with nocturnal or intrinsic asthma.
For a patient who is conscious, a better alternative anticholinergic agent
is intravenous glycopyrrolate.
* Possible overdose with an anticholinergic agent
such as a tricyclic antidepressant or a variety of mushroom.
In a randomized, placebo-controlled, crossover trial, 21 cognitively intact elderly persons were given doses of placebo or Artane (trihexyphenidyl), a muscarinic anticholinergic agent
with documented adverse effects on diverse cognitive functions.
This anticholinergic agent
, which blocks the muscarinic acetylcholine receptor in the lung and reduces mucus secretion without systemic absorption or side effects, is useful in those with moderate and severe asthma when given along with the first nebulized dose of a bronchodilator such as albuterol, Dr.
The combination of a [beta]-adrenergic and an anticholinergic agent
in COPD provides the rapid onset of action of the former and the sustained activity of the latter with the increased potency of their combined actions.
include medicines for urinary incontinence, motion sickness, and stomach cramps.
As a quaternary amine, it is hydrophilic and less likely to cross the blood-brain barrier and, theoretically, may be less likely to cause confusion, somnolence, and mental status changes in elderly than other anticholinergic agents
, he said.