Anticonvulsant

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anticonvulsant

[‚an·tē·kən′vəl·sənt]

(pharmacology)

An agent, such as Dilantin, that prevents or arrests a convulsion.

Anticonvulsant

one of a group of medicinal preparations having different chemical compositions and capable of preventing or relieving convulsions. Anticonvulsants include a number of substances that act as hypnotics and sedatives, for instance, bromides, chloral hydrate, magnesium sulfate, and phenobarbital. Other substances are selectively anticonvulsant, for example, diphenin, Hexamidine (lepsiral), Trimethin (epidione), and chloracon. Anticonvulsants are used mainly in treating epilepsy.

REFERENCE

Mashkovskii, M. D. Lekarstvennye sredstva, 7th ed., part 1. Moscow, 1972.

References in periodicals archive ?

Hyperhomocysteinemia in epileptic patients on new antiepileptic drugs.

Correlation between Hyperhomocysteinemia and Common Carotid Artery Intima media Thickness in Carbamazepine treated Epileptic patients using Ultrasonography

This analysis showed that the frequency of seizure increases was significantly greater with hormonal contraceptive use, compared with nonhormonal methods, across all five subgroups of antiepileptic drug type.

Hormonal contraceptives can increase seizures in women with epilepsy: risk appears greatest with valproate

Table showing total recipient, mean dose, mean duration of therapy, mean drug level and incidence of adverse effects of antiepileptic drugs.

Seizures and epilepsy in elderly: a tertiary care centre hospital based study

Fycompa is an antiepileptic drug that reduces neuronal hyperexcitation associated with seizures by targeting glutamate activity at postsynaptic AMPA receptors.

U.S. FDA Accepts sNDA For Antiepileptic Agent Fycompa as Adjunctive Treatment of Primary Generalized Tonic-Clonic Seizures

Referrals to a specialist owing to developmental delay (particularly for fine motor skills and social skills) were increased for children of mothers who used antiepileptic drugs.

Safety of antiepileptic medication in breastfeeding

Idiosyncratic adverse reactions to antiepileptic drugs.

Patients in the study who withdrew from antiepileptic drug (AED) treatment were not significantly more likely to have seizure recurrence than were those who did not, thereby meeting the common secondary goal of discontinuing or reducing AEDs after epilepsy surgery Thus, the findings of this study may provide reassurance to neurologists who are hesitant to withdraw AEDs after surgery because of concerns that seizures may recur, Dr.

Postsurgery antiepileptic reduction safe for children

The Neurodevelopmental Effects of Antiepileptic Drugs (NEAD) study, conducted in the United States and the United Kingdom, included pregnant women with epilepsy who were on AED monotherapy.

Nursing while taking antiepileptic drugs appears safe

Autism spectrum disorders following in utero exposure to antiepileptic drugs.

Does in utero exposure to valproate increase the risk of autism?

Since women in the study were taking antiepileptic drugs throughout pregnancy, it is unclear whether the effects on IQ are related to the timing or duration of prenatal valproate exposure, so "exposure to valproate at any time during pregnancy should be considered to have the potential to result in decreased IQ in children," the advisory says.

FDA: Antiseizure drugs unsafe in pregnant migraine patients

Antiepileptic drugs (AEDs) are increasingly used for the treatment of several non-epileptic neurological conditions and psychiatric disorders [2].

Effects of carbamazepine on serum parathormone, 25-hydroxyvitamin D, bone specific alkaline phosphatase, C-telopeptide, and osteocalcin levels in healthy rats

In terms of pharmacological management, the authors provide rationale for selection of antiepileptic drugs specific to seizure type, along with need for monotherapy versus combination therapy.

Fast Facts: Epilepsy

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