Antifungal

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Antifungal

a medicinal preparation used to treat such fungal diseases as dermatomycoses, onychomycoses, and candidiasis. Externally, antifungals are applied locally to the focus of the infection in the form of ointments, solutions, and other medicines. They are used to remove skin epidermis, hair, and nails infected by a fungus (salicylic and lactic acid preparations). Other antifungals suppress fungal growth (Amicazol [Asterol Dihydrochloride], Zincundan, and Nitrofungin). Systemic antifungals either kill fungi or inhibit their reproduction when taken orally (griseofulvin, nystatin, Levorin) or when injected intravenously (amphotericin B).

References in periodicals archive ?

Considering the above, we have developed a mild formulation based on substances derived 4H-pyrido[4',3':5,6] pyrano[2,3-d]pyrimidine derivatives with antifungal activity.

Development of gel composition and technology based on pyrimidine substance

Isavuconazole is an intravenous and oral azole antifungal that has marketing authorisation in Europe for the treatment of adult patients with invasive aspergillosis and as a treatment for adult patients with mucormycosis for whom amphotericin B is inappropriate.

Licence agreement between Basilea and Pfizer for antifungal Cresemba is complete

Lidocaine (LD) is an anesthetic used in clinical medicine, which showed antifungal activity has already been described, alone or in synergy with antifungal agents like amphotericinB, itraconazole, voriconazole, and caspofungin, however it is important to emphasize that the use must be topical due to toxicity (Judd & Martin, 2009; Palmeira-de-Oliveira et al., 2012; Rodrigues, Araujo, & Pina-Vaz, 2006).

In vitro synergistic activity of lidocaine and miconazole against Candida albicans/Atividade sinergica in vitro de lidocaina e miconazole contra Candida albicans

Wheat and her associates recommend a single-agent topical antifungal to treat superficial fungal infection.

Combo antifungal/corticosteroid creams contraindicated

The antifungal susceptibility profile of Candida species was determined using the Vitek 2 Systems Version 07.01 (Biomeriex, South Africa) following the CLSI document M27-A3 (2015) (16).

Species distribution and antifungal susceptibility patterns of Candida isolates from a public tertiary teaching hospital in the Eastern Cape Province, South Africa

The firm recommends buying Cidara shares given the removal of the financing overhang as well as an improving reimbursement environment for antibacterials and antifungals.

Wedbush Recommends Buying Cidara Shares After Rezafungin Deal

species.9 Recently, the Clinical and Laboratory Standards Institute (CLSI) described that the clinical efficacy of each antifungal agent relates to the MIC as it gives the MIC breakpoint for susceptibility of <2ug/ml for C.

Determination of minimum inhibitory concentrations of various antifungal agents in clinical isolates of Candida species

The paper 'In vitro antifungal activity of a novel topical triazole PC945 against emerging yeast Candida auris' (available to view here) outlines the susceptibility of C.auris to Pulmocide's novel antifungal triazole, PC945, optimized for topical delivery.

Pulmocide announces Journal of Antimicrobial Chemotherapy publication of novel antifungal PC945 activity against Candida auris, a health threat gaining global prominence

Surprisingly, it showed more promise than the antifungal drug, fluconazole.

Candidiasis: Foods To Eat To Fight Yeast Infection

Both creams also contained antibiotics and antifungal ingredients.

Singapore warns against four skin creams including one from Malaysia after infant hospitalised

They have a great diversity of antimicrobial activity, including antifungal and antibacterial activity [8-12].

Design, Synthesis and Evaluate In Vitro Antifungal Activity of Novel Benzamide Derivatives

In this study, we investigated in vitro antifungal activity of green tea and quince leaf on Candida isolates obtained from blood cultures.

In vitro Antifungal Activities of Fluconazole, Camellia sinensis and Cydonia oblonga Leaf Extracts Against Candida Species Isolated from Blood Cultures