Antifungal

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Antifungal

 

a medicinal preparation used to treat such fungal diseases as dermatomycoses, onychomycoses, and candidiasis. Externally, antifungals are applied locally to the focus of the infection in the form of ointments, solutions, and other medicines. They are used to remove skin epidermis, hair, and nails infected by a fungus (salicylic and lactic acid preparations). Other antifungals suppress fungal growth (Amicazol [Asterol Dihydrochloride], Zincundan, and Nitrofungin). Systemic antifungals either kill fungi or inhibit their reproduction when taken orally (griseofulvin, nystatin, Levorin) or when injected intravenously (amphotericin B).

References in periodicals archive ?
glabrata are regarded as intrinsically resistant species against azole antifungals.
We aimed to define a risk stratification parameter to guide a comprehensive diagnostic approach, helping the decision to start antifungal therapy in high-risk neutropenic patients.
Ian Nicholson, F2G's CEO commented: “F901318 is a significant addition to the antifungal armamentarium as there have not been any new classes of antifungal agents s approved for many years and growing resistance presents a considerable challenge in this seriously ill patient population.
Recurrent or persistent candidemia in patients on antifungal therapy is suggestive of an infected intravascular device, significant immunosuppression, or antifungal resistance.
The echinocandins, first novel class of antifungals in two decades: will they live up to their promise?
Hence, it seems reasonable to assume that most of the azole antifungals used in agriculture and medicine as well as azoles used in management of breast cancer also act as inhibitors on human sterol 14[alpha]-demethylase to an unknown extent.
One in four women using over-the-counter antifungal infection medications doesn't have a yeast infection, Dr.
The number of treatments is large and varied: frequent diaper changes, airing out the area by eliminating diapers whenever possible, super-absorbent diapers, disposable diapers, applying barrier creams and ointments, using corticosteroid creams, and topical antifungal agents when Candida albicans fungal infections.
Objective: To determine Candida colonisation/infection in renal transplant patients and to determine the resistance pattern against antifungal drugs.
com)-- F2G Limited, the UK based antifungal drug discovery and development company, today announced the appointment of Dr Michael R.
SAN DIEGO -- AIDS patients treated for cryptococcosis can safely stop their maintenance antifungal therapy once they have reconstituted their immune systems using antiretroviral drugs, results of a French study suggest.
In an open-label trial of 69 immunocompromised patients aged 18-80 years with invasive aspergillosis who were refractory to or intolerant of other antifungals, 41% (26) of the 63 patients who received at least one dose of Cancidas had complete resolution or clinically meaningful improvement.