antigenic determinant

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antigenic determinant

[‚an·tə¦jen·ik di′tər·mə·nənt]
(immunology)
The portion of an antigen molecule that determines the specificity of the antigen-antibody reaction.
References in periodicals archive ?
Kolaskar and Tongaonkar antigenicity scale for prediction of antigenic determinants in ACTTS protein in ARC (A), AWR (B) and AYC (C).
It is generally believed that most of identified linear antigenic determinants are parts of the conformational B-cell epitopes [8-10].
The positions of the Asparagines (N) that were identified as potential N-glycosylation sites and which are a part of the reported antigenic determinants are highlighted in bold in Table 5 because this is a factor that may contribute to the induction of an immune response by both phytases [39].
Analysis of the antigenic determinant groups of the mannan of Candida albicans serotype A.
As all the surface SGPs act as blood group antigenic determinants and receptor sites for viruses, bacteria and parasites, the presence of higher number of SGPs within the membrane of goat, buffalo and pig erythrocyte indicates the higher immunological response of the animals as compared to human.
These CAP-RASTs are 80-90% specific, with a lower sensitivity, but react only with the major antigenic determinants (allergy to minor determinants is tested by skin prick testing).
The [Centocor.sup.R] CA 72-4[TM} assay (Fujirebio Diagnostics, Inc./Centocor, Inc.) is a solid phase radioimmunoassay (CA 72-4) (RIA) based on two monoclonal antibodies, cc49 and B72.3, which react with distinct antigenic determinants on a tumor associated glycoprotein TAG 72.
VP1 residue 145 has previously been identified as a key antigenic determinant, of which substitution can significantly affect the neutralizing activity (23,38).
Use of multiple antigenic peptides related to antigenic determinants of infectious bursal disease virus (IBDV) for detection of anti- IBDV-specific antibody in ELISA-quantitative comparison with native antigen for their use in serodiagnosis.
Using vesicular stomatitis virus and prostate and melanoma derived libraries, this is curative in mice and we have established its mechanisms and the key antigenic determinants (Nature Medicine, Nature Biotechnology).