Anthelmintic

(redirected from Antihelminthic)
Also found in: Dictionary, Thesaurus, Medical.
Related to Antihelminthic: Albendazole, Antihelminthic Drugs

anthelmintic

[¦an·thel¦min·tik]
(pharmacology)

Anthelmintic

 

(also vermifuge, helminthagogue), a preparation used to treat worm diseases, or helminthiases. The action of different anthelmintics varies. Some preparations, such as Heptylresorcine and Phenasal, damage the cuticle (integument) of helminths, while other preparations, such as santonin, ditrazin, piperazine, and naphtammone, alter the tone and mobility of parasites. Anthelmintics expel helminths from the patient’s body and are used when helminths infest the intestine and its communicating organs (liver, pancreas). Anthelmintics are also used to kill helminths.

Piperazine acts on the neuromuscular system of ascarids, which are subsequently excreted with feces. Phenasal destroys the integument of various tapeworms, including beef tapeworms, dwarf tapeworms, and broad tapeworms. They are then digested in the intestine and their residue is excreted. Chloxyl kills Siberian liver fluke in the liver and pancreas. The parasite is then eliminated into the intestine. Other anthelmintics, such as ditrazin and antimony preparations, destroy helminths, such as filiariae and schistosomes, in the blood, lymphatics, and tissues. Some antihelmintics, such as ditrazin and Chloxyl, are produced chemically. Others are obtained from plants, for example, from Artemisia cina or the extract of male fern.

REFERENCE

Krotov, A. I. Osnovy eksperimental’noi terapii gel’mintozov. Moscow, 1973.

N. N. PLOTNIKOV

References in periodicals archive ?
The inclusion criteria were not pregnant patients, non-medicated with any of antihelminthic drugs, non-medicated with any of antibiotic, phenytoin, carbamazepine, no complication of gastrointestinal symptoms, no hepatitis or liver diseases.
They also might prevent or alleviate paradoxical worsening after initiation of antihelminthic treatment.
Albendazole is a potent antihelminthic drug widely used for the control of human as well as animal helminthes.
If these factors might intensify parasite transmission, the implementation of basic sanitation associated with the widespread use of antihelminthic drugs, often cheap and readily available in the health services, might help to reduce prevalence.
Toxicity, antihelminthic and electromyographic studies of methanolic extracts of Tephrosia vogelii.
33%) utilized medication with antihelminthic or antiprotozoal activity up to one month before the FPE, while among the 24 patients with positive FPE, only two utilized this type of medication, albeit at doses below those recommended; the difference was statistically significant (p<0.
In contrast, hookworm infection is diagnosed by demonstrating ova in stool, which are routinely excreted, or the adult male and female worms which can be recovered after antihelminthic treatment.
Prevalence and intensity by Direct Method: Levamex (containing 40 mg of Levamisole and manufactured by UNiBiOS Laboratories Ltd, india) a broad-spectrum antihelminthic was administered to all participants in the study according to manufacturer's instructions.
trichiura eggs after antihelminthic treatment with mebendazole (5), thiabendazole (6), tetracloroethylene (7) or dithiazanine (8).
Antihelminthic drugs for treating worms in children: effects on growth and cognitive performance.
The patient's condition improved after antihelminthic therapy with albendazole and antibiotics was initiated.
Levamisole, an antihelminthic agent, although no longer available in the US, has been used alone or in combination when patients are dependent on high-dose steroids or alkylating agents and fail to maintain remission.