Tefferi, "Use of fondaparinux in a patient with antiphospholipid antibody
syndrome and heparin-associated thrombocytopenia," Journal of Thrombosis and Haemostasis, vol.
The patient had a right atrial thrombus and antiphospholipid antibody
. The thrombosis was resolved through the administration of thrombolytic therapy.
Treatment of antiphospholipid antibody
syndrome (APS) in pregnancy: a randomized pilot trial comparing low molecular weight heparin to unfractionated heparin.
Myasthenia gravis, multiple sclerosis, antiphospholipid antibody
syndrome, Graves' disease, scleroderma, and hemolytic anemia are other ADs that affect women more than men.
The most common cause of digital gangrene associated with SLE is antiphospholipid antibody
syndrome (AAS), and SLE is the leading cause of secondary AAS.
syndrome (APS) is a systemic, autoimmune, acquired disorder characterized by venous and/or arterial thrombosis and/or pregnancy morbidities, associated with the positivity, confirmed at least in two occasions 12 weeks apart, of such autoantibodies directed toward molecular complexes of phospholipids and proteins.
A randomized controlled trial, the Antiphospholipid Antibody
Acetylsalicylic Acid (APLASA) study, failed to demonstrate reduction in thrombotic events with aspirin (ASA) compared to placebo, but likely is not generalizable to all lupus populations.
Among the specific cases are post-traumatic compartment syndrome, upper extremity deep vein thrombosis, lymphedema, antiphospholipid antibody
syndrome-induced ulceration, brown recluse spider bite, hemangioma of infancy, and limb ulceration due to malignant melanoma.
Sneddon's syndrome: An antiphospholipid antibody
The antiphospholipid antibody
syndrome (APLS) is the most important treatable cause for recurrent miscarriage.
Recent studies showed that total antioxidant status in the plasma was decreased (8, 9), serum antiphospholipid antibody
levels were elevated, which is a risk factor for cardiovascular and cerebrovascular diseases (10), connective tissue growth factor was increased (11) in patients with PEX.