Antispasmodic


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.
Related to Antispasmodic: Antispasmodic Drugs

antispasmodic

[¦an·tē‚spaz′mäd·ik]
(pharmacology)
An agent, such as benzyl benzoate, that relieves convulsions and the pain of muscular spasms.

Antispasmodic

 

one of a group of pharmacological substances with various chemical structures that induce the relaxation of the smooth muscles of, for example, the blood vessels, bronchi, and gastrointestinal, biliary, and urinary tracts.

Antispasmodics may be, according to their mechanism of action, neurotropic or musculotropic. Neurotropic agents include cholinolytics, for example, such m-cholinolytics as atropine, spasmolytin, thiphen, aprophen, and diprophen. Conventionally, they also include sympathomimetics (Adrenalin, ephedrine, Is-adrine [Aleudrin]), which relax the smooth muscles of the bronchi, intestines, and other organs by exciting sympathetic nerves. Musculotropic antispasmodics, including papaverine and drotav-erinum, directly act on the smooth muscles.

Antispasmodics are used to treat many diseases accompanied by the intensified contraction of the smooth muscles, including asthma, renal colic, and spasms of the cerebral blood vessels.

REFERENCES

Kuznetsov, S. G., and S. N. Golikov. Sinteticheskie alropinopodobnye veshchestva. Leningrad, 1962. (Bibliography.)
Wesselius de Casparis, A. “Neurotropic Versus Musculotropic Antispasmodics.” Medicamundi, 1962, vol. 8, no. 5, pp. 92–98. (Bibliography.)

V. V. ZAKUSOV

References in periodicals archive ?
Assessment of antispasmodic effect of herbal medicine, Shakuyakukanzo-to (TJ-68) by direct spraying during colonoscopy.
The aim was to perform a pharmacological antispasmodic testing (two models) of an ethanolic extract of P.
The antispasmodic effects of peppermint oil have been directly demonstrated in vitro in a series of experiments with smooth muscle fibres isolated from the guinea pig, including the trachea and ileum (Reiter and Brandt, 1985; Taddei et al.
This discovery enlarges the list of pharmacological effects already described for EOAz, which include antispasmodic (Bezerra et al.
Contract awarded for anticholinergic drug procurement, antispasmodic and antibacterial to be used in different services for the national hospital san benito, peten
See your doctor for a course of antidiarrhoeal drugs and antispasmodic drugs may relieve muscle spasms.
For use as adjunctive therapy in the treatment of irritable bowel syndrome (IBS) and acute enterocolitis, Donnatal(R) Elixir Grape is now a great tasting immediate release, antispasmodic therapy available only by prescription.
n Water retention: Golden Rod (Solidago) is a traditional diuretic and kidney tonic, with anti-inflammatory, antispasmodic and antiseptic action
Koek and his colleagues decided to treat patients with PPI therapy and baclofen, a [gamma]-aminobutyric acid type B receptor agonist / antispasmodic that has been shown to inhibit transient lower esophageal sphincter relaxation.
Dicyclomine HCl is a generic version of Hoechst Marion Roussel's, Bentyl(R), an antispasmodic and anticholinergic agent and is fully interchangeable with Bentyl(R).
Sesquiterpenes are thought to have antispasmodic and anti-inflammatory actions.
An antispasmodic and anticholinergic agent, the Lannett version of Bentyl(R) relieves muscle spasm of the gastrointestinal tract and is indicated for the treatment of functional bowel/irritable bowel syndrome.