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An agent, such as benzyl benzoate, that relieves convulsions and the pain of muscular spasms.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



one of a group of pharmacological substances with various chemical structures that induce the relaxation of the smooth muscles of, for example, the blood vessels, bronchi, and gastrointestinal, biliary, and urinary tracts.

Antispasmodics may be, according to their mechanism of action, neurotropic or musculotropic. Neurotropic agents include cholinolytics, for example, such m-cholinolytics as atropine, spasmolytin, thiphen, aprophen, and diprophen. Conventionally, they also include sympathomimetics (Adrenalin, ephedrine, Is-adrine [Aleudrin]), which relax the smooth muscles of the bronchi, intestines, and other organs by exciting sympathetic nerves. Musculotropic antispasmodics, including papaverine and drotav-erinum, directly act on the smooth muscles.

Antispasmodics are used to treat many diseases accompanied by the intensified contraction of the smooth muscles, including asthma, renal colic, and spasms of the cerebral blood vessels.


Kuznetsov, S. G., and S. N. Golikov. Sinteticheskie alropinopodobnye veshchestva. Leningrad, 1962. (Bibliography.)
Wesselius de Casparis, A. “Neurotropic Versus Musculotropic Antispasmodics.” Medicamundi, 1962, vol. 8, no. 5, pp. 92–98. (Bibliography.)


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
It is easy to use and handle, and with proper antispastic measures, will provide satisfactory mid- and long-term patency rates.
Comparison of the antispastic and endothelium-protective features of papaverine, varapamil and glyceryl trinitrate Papaverine Verapamil GT (undiluted) OnsetF of effect + ++ +++ Duration of effect ++ +++ Spasm prevention + ++ - Spasm reversal + ++ +++ Block of receptor-mediated + - +++ contraction ([alpha]1, TXA2 receptor) Blockade of depolarizing ++ +++ ++ agent-mediated contraction (K+) pH of solution Acidic Neutral Protection of endothelium + +++ None or weak (-); medium (+); strong (++); extra strong (+++) GT- glyceryl trinitrate Table 2.
The patients with stroke were not using antispastic medication during the study.
The same association is present in case of antispastic medication, too.
We may say the same thing about the antispastic medication administration, wich was less for experimental group, towards the control group.
Regarding the labor parameters, they showed an improvment in labor deployment to the pregnant women from experimental group, translated through decreasing of labor and delivery period, a decreasing of drugs administration (pain killers and antispastic madication) and a decreased level of pain.
Muscle cramps in chronic liver diseases and treatment with antispastic agent (eperisone hydrochloride).
Antispastic medications may have affected the magnitude of reflex responses for some subjects in the current study.
Cannabis extract is found to act in synergy as antispastic agent in mice than tetrahydrocannabinol at an equivalent dose (Baker et al., 2000; cit.
Antispastic medications, such as botulinum toxin, have been used successfully to reduce muscle spasticity, but their effects on motor functional improvement are still under debate [37-40].
Antispastic effect of electroacupuncture and moxibustion in stroke patients.
If these cannot be safely controlled, bronchial antispastics and budesonide nebulizer can be used *Invasive mechanical ventilation requires air heating and humidification during the whole process.