(redirected from Antispastic)
Also found in: Dictionary, Thesaurus, Medical.


An agent, such as benzyl benzoate, that relieves convulsions and the pain of muscular spasms.



one of a group of pharmacological substances with various chemical structures that induce the relaxation of the smooth muscles of, for example, the blood vessels, bronchi, and gastrointestinal, biliary, and urinary tracts.

Antispasmodics may be, according to their mechanism of action, neurotropic or musculotropic. Neurotropic agents include cholinolytics, for example, such m-cholinolytics as atropine, spasmolytin, thiphen, aprophen, and diprophen. Conventionally, they also include sympathomimetics (Adrenalin, ephedrine, Is-adrine [Aleudrin]), which relax the smooth muscles of the bronchi, intestines, and other organs by exciting sympathetic nerves. Musculotropic antispasmodics, including papaverine and drotav-erinum, directly act on the smooth muscles.

Antispasmodics are used to treat many diseases accompanied by the intensified contraction of the smooth muscles, including asthma, renal colic, and spasms of the cerebral blood vessels.


Kuznetsov, S. G., and S. N. Golikov. Sinteticheskie alropinopodobnye veshchestva. Leningrad, 1962. (Bibliography.)
Wesselius de Casparis, A. “Neurotropic Versus Musculotropic Antispasmodics.” Medicamundi, 1962, vol. 8, no. 5, pp. 92–98. (Bibliography.)


References in periodicals archive ?
Drawn by the thesis that an ideal method for preservation of the RA for CABG should be antispastic and also allow maximum preservation of the endothelial function, He and associates have compared the antispastic (36) and the endothelium-protective features (37) of the verapamil-nitroglycerin (VG) vs Papaverine solution.
The patients with stroke were not using antispastic medication during the study.
Eperisone hydrochloride is a novel antispastic agent, which has been developed in Japan and is now marketed in Japan, India and the Far East under the brand name Myonal[degrees].
Consider deterring spasticity with antispastic positioning, range of motion exercises, stretching, and splinting.
It has very low toxicity and is a safe and effective antispastic agent.