and fasciotomy/debridement in the treatment of the severe rattlesnake bite.
Following the listing in the WHO database, we are also expecting antivenin exportation to Europe and North America.
It should be considered that antivenin treatment can be more hazardous than the snake poison itself (8).
Using monovalent antivenin is preferred as it is more efficacious and cost effective and has less risk of adverse reactions due to the smaller volume required for treatment as compared to polyvalent.
The method of administration of antivenin may depend slightly on manufacturer instructions.
Recently, the nonprofit French drug firm Sanofi Pasteur had ceased the production of Fav-Afrique, the most effective antivenin against Africa's vipers, mambas, and cobras.
Due to the high cost, long production period, limited categories, short storage life, and common clinical side-effects of current antivenin, scientists have attempted to create antidotes from herbal extracts, marine compounds, mammalian and snake serum, and modified chemical molecules and peptides .
When combined, the seven active chemicals identified in the plants performed well in standard antivenin tests, Asuzu reported.
His team is now looking for international collaborators to begin testing the multicomponent antivenin in lab animals.--J.R.
That's because the two commercially marketed antivenins (sometimes called antivenoms) for U.S.
snake antivenins poses a life-threatening risk, both remain far from ideal -- triggering a generalized and sometimes severe immunological reaction called serum sickness in about 75 percent of recipients.
The patient was thus able to provide the first responders with detailed information about the snake and on where to obtain the corresponding antivenin
. He instructed his wife to apply a pressure bandage to the forearm.