Table-II: Serum concentrations in infants receiving caffeine and theophylline for apnea of prematurity.
Maria S, et al12 also conducted a study on comparison of caffeine and Theophylline when used in apnea of prematurity and reported that caffeine is superior to Theophylline when used early stages of prematurity infants < 33 weeks.
The differences in long-term outcomes of infants with apnea of prematurity vs infants without it are subtle, if present at all.
Apnea of prematurity, sudden infant death syndrome, and apparent life-threatening events.
Apnea of prematurity
is commonly treated with therapeutic caffeine, but the long-term effects of caffeine on sleep in the developing brain are not well understood.
Timely interpretation is essential for differentiating diagnoses and for medication adjustment, especially in light of the recent findings of the benefits of the use of caffeine in apnea of prematurity
in preventing long-term pulmonary and neurodevelopmental consequences of prematurity (Schmidt et al., 2007; Stevenson, 2007).
While caffeine and other methylxanthines have been used as respiratory stimulants for apnea of prematurity
for more than 30 years, these findings show for the first time that the benefits of caffeine therapy "outweigh any potential risks up to 2 years after very preterm birth," the investigators said.
Use of caffeine in infants unresponsive to theophylline in apnea of prematurity
. Pediatr Pulmonol.
-- A head-to-head comparison of four nasal continuous positive airway pressure devices for apnea of prematurity
indicated that devices employing "infant flow driver" technology are significantly superior to a standard intermittent mechanical ventilation device and are at least as good as an underwater bubble system.
Apnea of prematurity
is not a proven risk factor for SIDS.
Specific to the respiratory system they cover such topics as apnea of prematurity
, asthma basics, asthma and teens, BPD, cystic fibrosis, cystic fibrosis and nutrition, managing asthma, meconium aspiration, persistent pulmonary hypertension of the newborn (PPHN), and transient tachypnea of the newborn (TTN).
Chapter 28 deals with major pulmonary disorders in the neonate such as transient tachypnea of the newborn, pneumonia, meconium aspiration and apnea of prematurity
while Chapter 29 covers congenital and surgical disorders that affect respiration.