apob

(redirected from Apo B-100)
Also found in: Medical.

apob

[′ā‚päb]
(meteorology)
An observation of pressure, temperature, and relative humidity taken aloft by means of an aerometeorograph; a type of aircraft sounding.
Mentioned in ?
References in periodicals archive ?
Typically, these methods measure both apo B-100 and apo B-48, but in fasting samples greater than 95% of apo Bin plasma is apo B-100 and almost all of it is associated with LDL (6).
Association of apolipoprotein B and nuclear magnetic resonance spectroscopy--derived LDL particle number with outcomes in 25 clinical studies: assessment by the AACC lipoprotein and vascular diseases division working group on best practices
Binding of LDLs to the LDLR is mediated by interactions between the LDLR and the Apo B-100 lipoprotein.
Identification of genes contributing to cardiovascular disease in overweight and obese individuals from West Virginia
The primary endpoint is the reduction in Apo B-100, the atherogenic lipoprotein in LDL (low-density lipoprotein), compared to placebo.
Metabolex Completes Patient Enrollment in Phase 2 Trial of MBX-8025 for Treatment of Dyslipidemia
We aimed to investigate the frequency of apo B-100 mutations (colon 3500) C9774T (Arg 3500 [right arrow] Trp) and G9775A (Arg 3500 [right arrow] Gln) in patients with atherosclerosis in comparison with healthy subjects.
Absence of apolipoprotein B-3500 mutation in Turkish patients with coronary and cerebrovascular atherosclerosis/Koroner ve serebrovaskuler aterosklerozlu Turk hastalarda apolipoprotein B-3500 mutasyonu yoklugu
30] Measuring apo B-100 and LDL-C concentrations in serum or plasma may be employed for CHD risk stratification.
The ubiquitous, lipids and related diseases: A laboratory perspective
5 are cleared from the plasma mostly by the kidney, whereas truncated apo B molecules with a size [greater than or equal to] 70% of that of apo B-100 are removed by the liver (1,2).
A 54-year-old diabetic man with low serum cholesterol
Preclinical and clinical testing of MBX-8025 indicates that the drug has the potential to improve a number of lipid parameters that are abnormal in different types of dyslipidemia, including high LDL (or "bad") cholesterol, high Apo B-100 (the atherogenic lipoprotein), low HDL (or "good") cholesterol and high triglycerides (fats).
Metabolex Begins Phase 2 Trial of MBX-8025 for Treatment of Dyslipidemia
We used the monoclonal antibody 4E6, which is directed specifically against an epitope in the apolipoprotein B-100 (apo B-100) moiety of oxLDL that is formed from the substitution of aldehydes for lysine residues in apo B-100.
Oxidized LDL and the risk of coronary heart disease: results from the MONICA/KORA Augsburg Study
He and his associates were the first to achieve complete synthesis of a plasma apolipoprotein (apo C-I); they also determined the complete cDNA and amino acid sequence of apo B-100, one of the largest proteins ever sequenced and a key protein in atherosclerosis.
Dr. Antonio Gotto, Jr. to Join Board of Directors and Scientific Advisory Board of Arisaph Pharmaceuticals
Apo B-100 is essential for the binding of LDL particles to the LDL receptor (LDLR) for cellular uptake and degradation (2).
Plasma proprotein convertase subtilisin/ kexin type 9: a marker of LDL apolipoprotein B-100 catabolism?
Gotto and his associates were the first to achieve the complete synthesis of a plasma apolipoprotein (apo C-I), and they also determined the complete cDNA and amino acid sequence of apo B-100, one of the largest proteins ever sequenced and a key protein in atherosclerosis and cardiovascular disease.
World Renowned Lipid Expert, Dr. Antonio M. Gotto, Joins the Board of Directors of Esperion Therapeutics, Inc
Turbidity is a source of interference in apo B immunoassays of lipemic samples, and cross-reactivity of apo B-100 antibodies with apo B-48 on chylomicrons can also produce interference.
Estimation of LDL-associated apolipoprotein B from measurements of triglycerides and total apolipoprotein B

Encyclopedia browser ?
Full browser ?