McConathy, "Electroimmunoassay, radioimmunoassay, and radial immunodiffusion assay evaluated for quantification of human apolipoprotein B
," Clinical Chemistry, vol.
Sniderman, "Reliability of low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B
measurement," Journal of Clinical Lipidology, vol.
Protein fractions of 270, 190, 135 and 100 kDa were found to be apolipoprotein B
, alphs-2-macroglobulin, ceruloplasmin and immunoglobulin heavy chain respectively.
Corresponding values for apolipoprotein B
were 4, 4, 4, 4, 4, 4, 5, and 6 mg/dL in individuals without diabetes, respectively, and 17, 16, 16, 16, 17, 18, 24, and 26 mg/dL in individuals with diabetes, respectively.
Using multivariate prediction models adjusting for nonlipid risk factors, the apolipoprotein B
to apolipoprotein A-I ratio was comparable with other standard lipid level ratios (eg, total cholesterol to HDL) in predicting CHD, but adding the test did not add additional predictive utility.
and AI distributions in the United States, 1988-1991: Results of the National Health and Nutrition Examination Survey III.
Plasma LDL, high-density lipoprotein (HDLe, [HCL.sup.2.C], apolipoprotein A-I and apolipoprotein B
levels were measured at the end of each period.
Plasma low-density-lipoprotein (LDL) cholesterol and apolipoprotein B
concentrations increased significantly (0.12 +/- 0.65 mmol/L, P less than 0.025; 0.06 +/- 0.12 g/L, P less than 0.0004, respectively) in the group that changed to decaffeinated coffee.
Others have proposed adding measures of apolipoprotein B
, apolipoprotein A-I, lipoprotein (a), or lipoprotein-associated phospholipase [A.sub.2] to the current risk prediction formulas to improve risk prediction.
The most pertinent results in the comparison were the significant increase in apolipoprotein B
, Ceruloplasmin, apolipoprotein A-I and transthyretin in the sera of patients of CMP compared to healthy subjects.
(apoB), a large amphipathic glycoprotein, plays a central role in human lipoprotein metabolism (2).
Familial defective apolipoprotein B-100: a mutation of apolipoprotein B
that causes hypercholesterolemia.