(27) Maintaining a balance between apoptotic cell death
and cell survival has been suggested as a possible survival mechanism of autophagy for germ cells.
LIPO caused less apoptotic cell death
on cochlear cells than CDDP at anti-tumoral doses, suggesting a lower toxicity in cochlear cells compared to CDDP.
Furthermore, licofelone induces more late apoptotic/necrotic cells death than early apoptotic cell death
in rat hepatoma cells.
Neuroprotective role of antidiabetic drug metformin against apoptotic cell death
in primary cortical neurons.
EGCG Prevented Diabetes-Induced Activation of Testicular Apoptotic Cell Death
Signaling via NRF2.
The PI3K/Akt/mTOR signaling pathway is overexpressed or activated in various tumors and may inhibit apoptotic cell death
and enhance survival and resistance to chemotherapy of cancer cells [30, 31].
Gemigliptin Attenuated Cisplatin-Induced Apoptotic Cell Death
. Apoptotic death of renal tubular cells plays a central role in the pathogenesis of cisplatin-induced nephrotoxicity .
Reperfusion induces myocardial apoptotic cell death
. Cardiovasc Res 2000; 45: 651-60.
Although glucocorticoids have been reported to induce myocardium preservation and protect podocytes against apoptosis [23, 24], glucocorticoids are mainly known to lead to apoptotic cell death
and reduce proliferation in a variety of cells, including INS-1 cells [2, 25].
When apoptotic cell death
is blocked by pancaspase inhibitors, death signals such as Fas ligand and TNF can trigger necroptosis as an alternative cell death pathway (5).
However, the effects of capsaicin in apoptotic cell death
and adipogenesis of BMSCs remain unclear.
In the study we found that treating the cells with 150 [micro]M 6-OHDA induced oxidative stress by initiating a sequence of events that reduce cellular activity leading to apoptotic cell death
. We showed that preconditioning PC12 cells by exposing them to a lower concentration of 6-OHDA for a short period before subsequent exposure to a higher concentration resulted in greater cell viability and therefore less cell death.